EXCEED THE SPACE PROVIDED. The objective of this training program is to provide postdoctoral fellows and graduate students with coursework and research experience in cellular and molecular aspects of cancer to prepare them for independent investigative careers in basic and translational cancer research. The program is integral to the cancer biology training at the University of California, San Francisco (UCSF). The faculty, the majority of whom are members of the UCSF Comprehensive Cancer Center, includes basic researchers, laboratory- based physician-scientists, and more applied clinician-investigators. These investigators share common interests in the multifaceted fields of cellular, molecular and structural biology applied to the understanding of mechanisms of cancer initiation, progression, diagnosis and therapy. The areas of education and research training will expose trainees to a spectrum of approaches, concepts and opportunities from altered gene and protein structure and expression, cancer microenvironment and immunity, cell cycling and signaling to differentiation and development. The goal of this approach is to further the understanding of cancer initiation and progression so that the trainees will have an appropriate perspective to approaching basic cancer research as well as to address, prevention, biomarkers and translation to patients. Pre- and post-doctoral trainees will join one of 51 research groups involved in studying these basic mechanisms. To broaden their experience, the trainees will have access to the regularly scheduled SPORE group meetings and seminars. Trainees will have access to all the academic resources available at UCSF. In this way, trainees will be provided with an in-depth research experience in an environment that covers the broad front of molecular and cellular cancer research. A seminar program, research-in-progress discussion and journal clubs complement the research training. Post-doctoral trainees must have a Ph.D. or equivalent degree in cell or molecular biology, genetics, biochemistry or applicable discipline, or an M.D., Ph.D. Trainees will receive a stipend for an average of 2 years, but will be part of the program throughout their training period of at least 3 years. The pre-doctoral trainees will be selected on the basis of past accomplishments and promise, course work, grades achieved, suitability for the research projects and a commitment to a research career. The program will embed postdoctoral and graduate student trainees within a larger group of other trainees and cancer investigators with in the host laboratories to make a significant critical mass of basic cancer researchers at UCSF. Upon completion of the program, it is anticipated that the trainees will continue careers in basic and translational cancer research in;academic institutions, governmental agencies or biotechnology industry. PERFORMANCE SITE ========================================Section End===========================================
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