Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
2T32CA009579-11
Application #
2007112
Study Section
Subcommittee G - Education (NCI)
Project Start
1987-05-01
Project End
2002-02-28
Budget Start
1997-09-09
Budget End
1998-02-28
Support Year
11
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Sanford-Burnham Medical Research Institute
Department
Type
DUNS #
009214214
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Komatsu, Masanobu; Ruoslahti, Erkki (2005) R-Ras is a global regulator of vascular regeneration that suppresses intimal hyperplasia and tumor angiogenesis. Nat Med 11:1346-50
Brown, Darren M; Ruoslahti, Erkki (2004) Metadherin, a cell surface protein in breast tumors that mediates lung metastasis. Cancer Cell 5:365-74
Majumdar, Mousumi; Vuori, Kristiina; Stallcup, William B (2003) Engagement of the NG2 proteoglycan triggers cell spreading via rac and p130cas. Cell Signal 15:79-84
Zou, June X; Liu, Yanqiu; Pasquale, Elena B et al. (2002) Activated SRC oncogene phosphorylates R-ras and suppresses integrin activity. J Biol Chem 277:1824-7
Abassi, Yama A; Vuori, Kristiina (2002) Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling. EMBO J 21:4571-82
Matter, M L; Ruoslahti, E (2001) A signaling pathway from the alpha5beta1 and alpha(v)beta3 integrins that elevates bcl-2 transcription. J Biol Chem 276:27757-63
Goretzki, L; Lombardo, C R; Stallcup, W B (2000) Binding of the NG2 proteoglycan to kringle domains modulates the functional properties of angiostatin and plasmin(ogen). J Biol Chem 275:28625-33
Zou, J X; Wang, B; Kalo, M S et al. (1999) An Eph receptor regulates integrin activity through R-Ras. Proc Natl Acad Sci U S A 96:13813-8
Connor, R J; Menzel, P; Pasquale, E B (1998) Expression and tyrosine phosphorylation of Eph receptors suggest multiple mechanisms in patterning of the visual system. Dev Biol 193:21-35
Matter, M L; Zhang, Z; Nordstedt, C et al. (1998) The alpha5beta1 integrin mediates elimination of amyloid-beta peptide and protects against apoptosis. J Cell Biol 141:1019-30

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