This training program for predoctoral, postdoctoral, and undergraduate trainees provides an interdisciplinary education and research experience in hearing, balance and chemical senses (HBCS). Predoctoral training is based in one of the 15 academic departments and degree-granting graduate programs with which the 28 training faculty are associated. Doctoral thesis research and postdoctoral research training reside primarily within the laboratories of the mentors. Our affiliated faculty provides outstanding training in each of their corresponding disciplines: bioengineering, cellular and molecular biology, genetics, molecular and neurophysiology, developmental biology, and biopsychology of sensory processing. The HBCS program integrates investigators in auditory, vestibular and chemosensory research with trainees from across these disciplines and thereby fosters innovative training opportunities into mechanisms and disorders of hearing, balance, taste and smell. Cross-disciplinary integration is made possible by the training program through: a) introductory and advanced courses in sensory systems;b) seminars in hearing, balance and chemical senses with experts from within and outside the University of Michigan;c) student and faculty seminars, journal clubs and research forums;d) exposure to clinical research issues in Otolaryngology and clinical/translational resources available at the University of Michigan Medical School, and d) training in research standards and ethics. Support for 5 predoctoral and 4 postdoctoral trainees is requested. Predoctoral trainees will be selected from the most highly qualified graduate students in the training faculty's affiliated departments and programs. Interest and motivation for research in sensory systems will be an important criterion. Postdoctoral trainees must have a doctoral degree such as a Ph.D. or M.D. and a strong commitment to sensory biology. Support is also requested to recruit hearing impaired individuals into biomedical research. The deaf are clearly underrepresented in scientific and medical professions. The goal of our Science Mentorship Program (SMP) is to provide these under-represented individuals with direct exposure to mainstream research in the sensory sciences in order to better prepare them for entry into graduate and professional schools. We propose to continue the SMP, begun in 1990, by training 5 deaf undergraduate students per year in summer research internships.

Public Health Relevance

Our primary goal for this training program is to attract promising scientists to the research fields of hearing, balance, taste and smell and to provide them with the mentoring and training that will result in their pursuit of productive research careers in these areas. A better understanding of these areas of sensory neuroscience will provide important insight into many human sensory disorders that greatly affect quality of life.

National Institute of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZDC1-SRB-L (47))
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Sklare, Dan
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University of Michigan Ann Arbor
Schools of Medicine
Ann Arbor
United States
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Heeringa, Amarins N; Wu, Calvin; Shore, Susan E (2018) Multisensory Integration Enhances Temporal Coding in Ventral Cochlear Nucleus Bushy Cells. J Neurosci 38:2832-2843
Marks, Kendra L; Martel, David T; Wu, Calvin et al. (2018) Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and humans. Sci Transl Med 10:
Altschuler, Richard A; Halsey, Karin; Kanicki, Ariane et al. (2018) Small Arms Fire-like noise: Effects on Hearing Loss, Gap Detection and the Influence of Preventive Treatment. Neuroscience :
Avenarius, Matthew R; Jung, Jae-Yun; Askew, Charles et al. (2018) Grxcr2 is required for stereocilia morphogenesis in the cochlea. PLoS One 13:e0201713
Dixon, Angela R; Ramirez, Yadah; Haengel, Kathryn et al. (2018) A drop array culture for patterning adherent mouse embryonic stem cell-derived neurospheres. J Tissue Eng Regen Med 12:e379-e383
Olney, Jeffrey J; Warlow, Shelley M; Naffziger, Erin E et al. (2018) Current perspectives on incentive salience and applications to clinical disorders. Curr Opin Behav Sci 22:59-69
Haggerty, Stephanie E; King, W Michael (2018) The Interaction of Pre-programmed Eye Movements With the Vestibulo-Ocular Reflex. Front Syst Neurosci 12:4
Schaefer, Stacy A; Higashi, Atsuko Y; Loomis, Benjamin et al. (2018) From Otic Induction to Hair Cell Production: Pax2EGFP Cell Line Illuminates Key Stages of Development in Mouse Inner Ear Organoid Model. Stem Cells Dev 27:237-251
Heeringa, Amarins N; Wu, Calvin; Chung, Christopher et al. (2018) Glutamatergic Projections to the Cochlear Nucleus are Redistributed in Tinnitus. Neuroscience 391:91-103
Stewart, Courtney E; Kanicki, Ariane C; Altschuler, Richard A et al. (2018) Vestibular short-latency evoked potential abolished by low-frequency noise exposure in rats. J Neurophysiol 119:662-667

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