? The purpose of this grant is to furnish basic and clinical research training for postdoctoral renal fellows with M.D. or M.D./Ph.D. degrees that wish to pursue biomedical research careers. Trainees entering our research laboratories will usually have completed a medical residency and one year of clinical nephrology. Selection for appointment is based on the aptitude of the applicant and their commitment to a career in biomedical research. Trainees are normally appointed for two years. Our program teaches a rigorous approach to scientific inquiry in basic science or/and clinical investigation. The faculty of this training program are all members of the University of Pennsylvania. Together they form a close and well-integrated collaborative entity dedicated to research training and investigation. The core basic research program emphasizes the areas of: immunology/inflammation, transplantation, kidney development and structural biology, and the pathogenesis of diabetic nephropathy, whereas the core clinical programs focus on the epidemiology of chronic kidney disease and hypertension. Trainees may elect to work with investigators outside the Renal Electrolyte and Hypertension Division, working in related areas. In either scenario, cross-fertilization and development of skills to prepare trainees for a life long investigative career are emphasized. Each trainee will develop a carefully crafted research project under the close supervision of a faculty trainer. This intensively structured research experience will be supplemented by research seminars, attendance at scientific meetings, and by formal course work in molecular genetics, immunology, biochemistry, cell biology, statistics, bioethics, environmental health, radiation safety and experimental design. The Renal Research Training Committee made up of the Program Directors will carefully monitor the evolving progress of each trainee. Upon completion of this comprehensive experience, it is anticipated that each graduate will be equipped to effectively compete for further individual training support, or for independent funding at an entry-level faculty position in academic nephrolog ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007006-34
Application #
7255662
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Rankin, Tracy L
Project Start
1975-07-01
Project End
2010-06-30
Budget Start
2007-07-01
Budget End
2008-06-30
Support Year
34
Fiscal Year
2007
Total Cost
$314,275
Indirect Cost
Name
University of Pennsylvania
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Levy Erez, Daniella; Copelovitch, Lawrence; Denburg, Michele (2018) Salt, sweat, and unclear? Diaphoresis and hypernatremia in end-stage kidney disease: Questions. Pediatr Nephrol 33:251-252
Louis, Robert; Levy-Erez, Daniella; Cahill, Anne Marie et al. (2018) Imaging studies in pediatric fibromuscular dysplasia (FMD): a single-center experience. Pediatr Nephrol 33:1593-1599
Levy Erez, Daniella; Copelovitch, Lawrence; Denburg, Michele (2018) Salt, sweat, and unclear? Diaphoresis and hypernatremia in end-stage kidney disease: Answers. Pediatr Nephrol 33:253-254
Muallem, Gaia; Wagage, Sagie; Sun, Yan et al. (2017) IL-27 Limits Type 2 Immunopathology Following Parainfluenza Virus Infection. PLoS Pathog 13:e1006173
Beckerman, Pazit; Bi-Karchin, Jing; Park, Ae Seo Deok et al. (2017) Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice. Nat Med 23:429-438
Lin, Jamie S; Susztak, Katalin (2016) Podocytes: the Weakest Link in Diabetic Kidney Disease? Curr Diab Rep 16:45
Bansal, Amar D; Negoianu, Dan; Warburton, Karen M (2016) An Unusual yet ""Mg""nificent Indication for Hemodialysis. Semin Dial 29:247-50
Chu, Carissa; Masic, Selma; Usawachintachit, Manint et al. (2016) Ultrasound-Guided Renal Access for Percutaneous Nephrolithotomy: A Description of Three Novel Ultrasound-Guided Needle Techniques. J Endourol 30:153-8
Clark, Stephanie L; Denburg, Michelle R; Furth, Susan L (2016) Physical activity and screen time in adolescents in the chronic kidney disease in children (CKiD) cohort. Pediatr Nephrol 31:801-8
Seshasai, Rebecca Kurnik; Mitra, Nandita; Chaknos, C Michael et al. (2016) Factors Associated With Discontinuation of Home Hemodialysis. Am J Kidney Dis 67:629-37

Showing the most recent 10 out of 199 publications