Abstract

This is an application for continued support of a training program in digestive diseases at the University of California at San Francisco (UCSF). The program objective is to provide highly selected individuals with clinical and basic research training leading to careers as independent investigators. The training program exists in the context of an interdisciplinary enterprise in digestive diseases with multiple components, including the Division of Gastroenterology, the Liver Center, and the Liver Transplantation Program. Training program leadership and key faculty include 17 Senior Faculty Mentors and 13 Junior Mentors holding faculty appointments in the Departments of Anatomy, Biochemistry, Medicine, Microbiology and Immunology, Pathology, Physiology, and Surgery based at all four major teaching hospitals of the University of California, San Francisco.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007007-25
Application #
2905025
Study Section
Special Emphasis Panel (SRC)
Program Officer
Podskalny, Judith M,
Project Start
1975-07-01
Project End
2000-06-30
Budget Start
1999-07-01
Budget End
2000-06-30
Support Year
25
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Issaka, Rachel B; Singh, Maneesh H; Rachocki, Carly et al. (2018) Missed Opportunities in Colorectal Cancer Prevention in Patients With Inadequate Bowel Preparations. Clin Gastroenterol Hepatol 16:1533-1534
Kattah, Michael G; Shao, Ling; Rosli, Yenny Y et al. (2018) A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival. J Exp Med 215:1839-1852
Alsayid, Muhammad; Singh, Maneesh H; Issaka, Rachel et al. (2018) Yield of Colonoscopy After a Positive Result From a Fecal Immunochemical Test OC-Light. Clin Gastroenterol Hepatol 16:1593-1597.e1
Issaka, Rachel B; Singh, Maneesh H; Oshima, Sachiko M et al. (2017) Inadequate Utilization of Diagnostic Colonoscopy Following Abnormal FIT Results in an Integrated Safety-Net System. Am J Gastroenterol 112:375-382
Whang, Michael I; Tavares, Rita M; Benjamin, Daniel I et al. (2017) The Ubiquitin Binding Protein TAX1BP1 Mediates Autophagasome Induction and the Metabolic Transition of Activated T Cells. Immunity 46:405-420
Kattah, Michael G; Malynn, Barbara A; Ma, Averil (2017) Ubiquitin-Modifying Enzymes and Regulation of the Inflammasome. J Mol Biol 429:3471-3485
Burns, Michael L; Malott, Thomas M; Metcalf, Kevin J et al. (2016) Pro-region engineering for improved yeast display and secretion of brain derived neurotrophic factor. Biotechnol J 11:425-36
Onizawa, Michio; Oshima, Shigeru; Schulze-Topphoff, Ulf et al. (2015) Erratum: The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis. Nat Immunol 16:785
Jensen, Christopher D; Doubeni, Chyke A; Quinn, Virginia P et al. (2015) Adjusting for patient demographics has minimal effects on rates of adenoma detection in a large, community-based setting. Clin Gastroenterol Hepatol 13:739-46
Ma, Averil (2015) From trash collectors to guardians of cell signaling and immune homeostasis. Immunol Rev 266:1-5

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