Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007018-17
Application #
3534590
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1978-09-30
Project End
1994-11-30
Budget Start
1991-12-01
Budget End
1992-11-30
Support Year
17
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Iowa
Department
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Shinozaki, Hiromitsu; Butnev, Viktor; Tao, Ya-Xiong et al. (2003) Desensitization of Gs-coupled receptor signaling by constitutively active mutants of the human lutropin/choriogonadotropin receptor. J Clin Endocrinol Metab 88:1194-204
Tao, Ya-Xiong; Mizrachi, Dario; Segaloff, Deborah L (2002) Chimeras of the rat and human FSH receptors (FSHRs) identify residues that permit or suppress transmembrane 6 mutation-induced constitutive activation of the FSHR via rearrangements of hydrophobic interactions between helices 6 and 7. Mol Endocrinol 16:1881-92
Tao, Y X; Abell, A N; Liu, X et al. (2000) Constitutive activation of G protein-coupled receptors as a result of selective substitution of a conserved leucine residue in transmembrane helix III. Mol Endocrinol 14:1272-82
LaCount, D J; Bruse, S; Hill, K L et al. (2000) Double-stranded RNA interference in Trypanosoma brucei using head-to-head promoters. Mol Biochem Parasitol 111:67-76
Amendt, B A; Sutherland, L B; Russo, A F (1999) Multifunctional role of the Pitx2 homeodomain protein C-terminal tail. Mol Cell Biol 19:7001-10
Amendt, B A; Sutherland, L B; Semina, E V et al. (1998) The molecular basis of Rieger syndrome. Analysis of Pitx2 homeodomain protein activities. J Biol Chem 273:20066-72
Hodnett, D W; Fantozzi, D A; Thurmond, D C et al. (1996) The chicken malic enzyme gene: structural organization and identification of triiodothyronine response elements in the 5'-flanking DNA. Arch Biochem Biophys 334:309-24
Kyllo, J H; Collins, M M; Vetter, K L et al. (1996) Linkage of congenital isolated adrenocorticotropic hormone deficiency to the corticotropin releasing hormone locus using simple sequence repeat polymorphisms. Am J Med Genet 62:262-7
Dhanwada, K R; Vijapurkar, U; Ascoli, M (1996) Two mutations of the lutropin/choriogonadotropin receptor that impair signal transduction also interfere with receptor-mediated endocytosis. Mol Endocrinol 10:544-54
Kyllo, J H; Collins, M M; Donohoue, P A (1995) Constitutive human steroid 21-hydroxylase promoter gene and pseudogene activity in steroidogenic and nonsteroidogenic cells with the luciferase gene as a reporter. Endocr Res 21:777-91

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