Completion of the Institute of Medicine's reviews of nutrient based dietary standards and publication of the 2005 Dietary Guidelines for Americans and Healthy People 2010underscore the high and growing importance of nutritional Sciences to improving the public's health. It is clear from these documents that the role of nutrition in promoting health and preventing chronic non-communicable diseases is second only to smoking prevention. The proposed program's objective is to meet the multidisciplinary demands inherent to the research questions of greatest relevance to nutritional Sciences.
Its specific aim i s to train over a 5 year period approximately 20 research leaders for academia, government and the private for-profit and non-profit sectors in the area of nutritional Sciences. A broad range of disciplines is necessary to address this objective and specific aim. These are represented among the proposed training staff, i.e., genetics, molecular biology and biochemistry through sociology, psychology and economics. Externally funded research to complement a strong didactic program is available. NIH funding has grown from a value of$2.1 million in 2000-01, to a value of $10 million in 2003-04. Presently, the Division has 18funded or pending NIH awards worth a total value of $18.5 million. External research support from other federal, state, international, and private sources substantially augment this base. Resources for the continuing annual support of 11 trainees are sought. In the last four years the infrastructure for supporting the proposed training program has been strengthened significantly by the acquisition of equipment key to the program's growing emphases in the nutritional genomics and tracer technologies, and more importantly by the recruitment and tenuring of key professionals with expertise in the biological and social sciences. The DNS' research and training capabilities have been strengthened in areas such as population genetics, computational and developmental biology, epigenetic regulation, dietary/gene/cancer interrelationships, micronutrient regulation of the immune system, domestic nutrition interventions targeting low income groups, and the economics of """"""""globalization's"""""""" impact on diets throughout the world. These new strengths and the program's documented contributions to the training of nutrition professionals presently in key positions in academia, government, and the for-profit and non-profit sectors support the training program's objectives and specific aims.
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|Hootman, Katie C; Guertin, Kristin A; Cassano, Patricia A (2018) Stress and psychological constructs related to eating behavior are associated with anthropometry and body composition in young adults. Appetite 125:287-294|
|Bae, Sajin; Chon, James; Field, Martha S et al. (2017) Alcohol Dehydrogenase 5 Is a Source of Formate for De Novo Purine Biosynthesis in HepG2 Cells. J Nutr 147:499-505|
|Ganz, Eric; Ganz, Ariel B; Yang, Li-Ming et al. (2017) The initial stages of melting of graphene between 4000 K and 6000 K. Phys Chem Chem Phys 19:3756-3762|
|Hootman, Katie C; Guertin, Kristin A; Cassano PhD, Patricia A (2017) Longitudinal changes in anthropometry and body composition in university freshmen. J Am Coll Health 65:268-276|
|Felice, Julia P; Geraghty, Sheela R; Quaglieri, Caroline W et al. (2017) ""Breastfeeding"" without baby: A longitudinal, qualitative investigation of how mothers perceive, feel about, and practice human milk expression. Matern Child Nutr 13:|
|Hootman, Katie C; Trezzi, Jean-Pierre; Kraemer, Lisa et al. (2017) Erythritol is a pentose-phosphate pathway metabolite and associated with adiposity gain in young adults. Proc Natl Acad Sci U S A 114:E4233-E4240|
|Ganz, Ariel B; Cohen, Vanessa V; Swersky, Camille C et al. (2017) Genetic Variation in Choline-Metabolizing Enzymes Alters Choline Metabolism in Young Women Consuming Choline Intakes Meeting Current Recommendations. Int J Mol Sci 18:|
|Wood, Madeleine R; Yu, Elaine A; Mehta, Saurabh (2017) The Human Microbiome in the Fight Against Tuberculosis. Am J Trop Med Hyg 96:1274-1284|
|Ganz, Ariel B; Klatt, Kevin C; Caudill, Marie A (2017) Common Genetic Variants Alter Metabolism and Influence Dietary Choline Requirements. Nutrients 9:|
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