This renewal proposal requests five additional years of support (years 33-38) for the University of California, Los Angeles Training Grant in Gastroenterology. Support is sought to maintain the trainees at the same level: six (either MD's or PhD's) and one additional minority candidate, for a total of seven positions per year. These trainees will be from the UCLA STAR (Specialized Training in Academic Research), the Affiliated UCLA Training Program in Gastroenterology, or from Affiliated Ph.D. training programs. This Training Grant has been funded continuously since 1974, and Dennis M. Jensen, M.D. has been the P.I./Director since 2000. During the last 10 years of this grant, 26 trainees have been enrolled in the program, 19 have completed training, and 7 will continue in the program after July 1, 2005. Of those who will have completed the program by June 30, 2005, 19 (100%) completed at least 1 1/2 years of research training, 89% completed 2 or more years of research training, 95% published at least one peer-reviewed research paper, and 84% obtained additional research training support or funding. In all, 14 (74%) have been a Principal Investigator of one or more NIH funded training or research grants, 2 (11%) have been awarded Veterans Administration research or career development grants, and 3 (16%) have been awarded other career development grants (CCFA or Cal Cancer Research Institute). In all, 16 (84%) have received such additional independent peer-reviewed funding. Among the 17 trainees who have completed their post-MD training, 14 (82%) hold academic positions and 1 (6%) holds a senior pharmaceutical position for a total of 88% in such leadership positions. The administrative structure of the Training Grant has evolved during the past five years to maximize productivity and satisfaction plus emphasize successful career paths for virtually all trainees. The leadership of this training grant is well balanced. The PI is a clinical and outcomes researcher, one co-PI is a basic scientist (Stephen Pandol, MD), and the other is a translational researcher (Peter Anton, MD). The Digestive Diseases Research Training Executive Committee ensures that all research trainees are closely supervised throughout their career development and are exposed to formal courses and research seminars to expand their scientific knowledge base. The UCLA STAR program has the added dimension of requiring Masters or Ph.D. degrees as part of the research training and career development. This training serves as the foundation and model for a highly evolved and successful UCLA Research Training Program in Gastroenterology. Continued support is needed to maintain the quality and productivity of this program which is training future academicians in digestive diseases.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007180-36
Application #
7881502
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Densmore, Christine L
Project Start
1976-07-01
Project End
2011-06-30
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
36
Fiscal Year
2010
Total Cost
$346,749
Indirect Cost
Name
University of California Los Angeles
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Videlock, Elizabeth J; Mahurkar-Joshi, Swapna; Hoffman, Jill M et al. (2018) Sigmoid colon mucosal gene expression supports alterations of neuronal signaling in irritable bowel syndrome with constipation. Am J Physiol Gastrointest Liver Physiol 315:G140-G157
Jacob, Noam; Jacobs, Jonathan P; Kumagai, Kotaro et al. (2018) Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome. Mucosal Immunol 11:1466-1476
Park, S H; Naliboff, B D; Shih, W et al. (2018) Resilience is decreased in irritable bowel syndrome and associated with symptoms and cortisol response. Neurogastroenterol Motil 30:
Xu, Mu; Jung, Xiaoman; Hines, O Joe et al. (2018) Obesity and Pancreatic Cancer: Overview of Epidemiology and Potential Prevention by Weight Loss. Pancreas 47:158-162
Dong, Tien; Pisegna, Joseph (2018) Passing the ""Acid Test"": Do Proton Pump Inhibitors Affect the Composition of the Microbiome? Dig Dis Sci :
Jacobs, Jonathan P; Lin, Lin; Goudarzi, Maryam et al. (2017) Microbial, metabolomic, and immunologic dynamics in a relapsing genetic mouse model of colitis induced by T-synthase deficiency. Gut Microbes 8:1-16
Benhammou, Jihane N; Phan, Jennifer; Lee, Hane et al. (2017) A Sodium Channel Myotonia Presenting with Intermittent Dysphagia as a Manifestation of a Rare SCN4A Variant. J Mol Neurosci 61:312-314
Wang, Jeremy; Benhammou, Jihane N; Ghassemi, Kevin et al. (2017) Endoscopic Ultrasound-Guided Fine Needle Aspiration Accurately Diagnoses Smaller Pancreatic Neuroendocrine Tumors Compared To Computer Tomography-Guided Fine Needle Aspiration. J Gastroenterol Pancreatol Liver Disord 4:1-7
Jackson, Samuel B; Villano, Nicholas P; Benhammou, Jihane N et al. (2017) Gastrointestinal Manifestations of Hereditary Hemorrhagic Telangiectasia (HHT): A Systematic Review of the Literature. Dig Dis Sci 62:2623-2630
May, Folasade P; Reid, Mark W; Cohen, Samuel et al. (2017) Predictive overbooking and active recruitment increases uptake of endoscopy appointments among African American patients. Gastrointest Endosc 85:700-705

Showing the most recent 10 out of 91 publications