The Division of Endocrinology and Diabetes at the University of Minnesota is requesting another 5 years of support for the training grant that has been funded for 29 continuous years. We are seeking support of post-doctoral research training in the fields of endocrinology, diabetes and metabolism. Training will provide in-depth research experience to recent PhD graduates or MD graduates who have completed a medicine or pediatric residency and wish to become academic physicians. Each principal trainer is an independent investigator with a national or international reputation. The program assures that all trainees receive appropriate exposure to contemporary techniques in cell biology, molecular biology or clinical investigation. Upon completion of the training, the trainee will be in an oustanding position to assume an academic career in a university or research institution. The major component of the program assures the maximal interaction between the trainee and the mentor. Additionally, the entire faculty and other trainees in the program are afforded the opportunity for interactions. Furthermore, physicians who have completed their residency requirements are provided additional training to fill in missing gaps in basic science education. Because the University of Minnesota, Fairview-University Medical Center, the Veterans Hospital and Hennepin County Medical Center provide funds to support the clinical training, all funds provided by this training grant are devoted to the research training of the physicians. However, at the end of their training, we anticipate that all physicians will attain board certification in endocrinology and that both PhD and MD trainees are sufficiently trained in academic research to successfully compete for federal funding and become productive academic scientists.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007203-33
Application #
7878651
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Castle, Arthur
Project Start
1977-08-01
Project End
2012-06-30
Budget Start
2010-07-01
Budget End
2012-06-30
Support Year
33
Fiscal Year
2010
Total Cost
$116,455
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Burrack, Adam L; Malhotra, Deepali; Dileepan, Thamotharampillai et al. (2018) Cutting Edge: Allograft Rejection Is Associated with Weak T Cell Responses to Many Different Graft Leukocyte-Derived Peptides. J Immunol 200:477-482
Muratore, Katherine A; Najt, Charles P; Livezey, Nicholas M et al. (2018) Sizing lipid droplets from adult and geriatric mouse liver tissue via nanoparticle tracking analysis. Anal Bioanal Chem 410:3629-3638
Bogachus, Lindsey D; Bellin, Melena D; Vella, Adrian et al. (2018) Deficient Glucagon Response to Hypoglycemia During a Mixed Meal in Total Pancreatectomy/Islet Autotransplantation Recipients. J Clin Endocrinol Metab 103:1522-1529
Osum, Kevin C; Burrack, Adam L; Martinov, Tijana et al. (2018) Interferon-gamma drives programmed death-ligand 1 expression on islet ? cells to limit T cell function during autoimmune diabetes. Sci Rep 8:8295
Burrack, Adam L; Landry, Laurie G; Siebert, Janet et al. (2018) Simultaneous Recognition of Allogeneic MHC and Cognate Autoantigen by Autoreactive T Cells in Transplant Rejection. J Immunol 200:1504-1512
Robinson, Jerid W; Egbert, Jeremy R; Davydova, Julia et al. (2017) Dephosphorylation is the mechanism of fibroblast growth factor inhibition of guanylyl cyclase-B. Cell Signal 40:222-229
Shuhaibar, Leia C; Robinson, Jerid W; Vigone, Giulia et al. (2017) Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor. Elife 6:
Bogachus, Lindsey D; Oseid, Elizabeth; Bellin, Melena et al. (2017) Deficient Endogenous Glucose Production During Exercise After Total Pancreatectomy/Islet Autotransplantation. J Clin Endocrinol Metab 102:3288-3295
Burrack, Adam L; Martinov, Tijana; Fife, Brian T (2017) T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes. Front Endocrinol (Lausanne) 8:343
Raymond, Christiana J; Bosch, Tyler A; Bush, Foster K et al. (2017) Accuracy and Reliability of Assessing Lateral Compartmental Leg Composition Using Dual-Energy X-ray Absorptiometry. Med Sci Sports Exerc 49:833-839

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