A. Purpose and Program Characteristics. The goal of this Research Training Program is to provide training in investigative hepatology to candidates interested in academic careers. The program is for a minimum of two years and stresses pathobiology of liver disease. All research and clinical training activities are interdisciplinary and involve established investigators in the Departments of Medicine, Molecular Pharmacology, Biophysics, Biochemistry, Cell Biology, Neurosciences and Anatomy and Structural Biology who share common research goals but whose conceptual and methodologic approaches differ greatly. Integration of this Training Program with activities of the Einstein Liver Research Center remains of paramount importance. There are 40 major investigators in the Liver Research Center, and they encompass a wide diversity in backgrounds, areas of expertise, interests and specific research projects. Liver Center investigators also serve as preceptors in the training program. The educational and collaborative programs of the Liver Research Center provide an ongoing structure for training future academicians in pathobiology of liver disease. Trainees have abundant opportunity to learn from outstanding authorities in their fields. Furthermore, basic scientists share disease-related interests and actively participate in the scientific activities of the Liver Research Center. The research training program includes the following five components: (a) scheduled weekly seminars, conferences and discussions, (b) specific course work in the Sue Golding Graduate School, (c) interdisciplinary collaborations with basic scientists, (d) attendance in ongoing activities of basic science and clinical departments at the Albert Einstein College of Medicine, and (e) specific sponsorship and training under the supervision of one or more experienced research scientists.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007218-26
Application #
6380244
Study Section
Special Emphasis Panel (ZDK1-GRB-B (01))
Program Officer
Podskalny, Judith M,
Project Start
1976-07-01
Project End
2002-03-31
Budget Start
2001-04-01
Budget End
2002-03-31
Support Year
26
Fiscal Year
2001
Total Cost
$108,711
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
009095365
City
Bronx
State
NY
Country
United States
Zip Code
10461
Scandiuzzi, Lisa; Ghosh, Kaya; Hofmeyer, Kimberly A et al. (2014) Tissue-expressed B7-H1 critically controls intestinal inflammation. Cell Rep 6:625-32
Liu, K; Czaja, M J (2013) Regulation of lipid stores and metabolism by lipophagy. Cell Death Differ 20:3-11
Zhao, Ruihua; Chinai, Jordan M; Buhl, Susan et al. (2013) HHLA2 is a member of the B7 family and inhibits human CD4 and CD8 T-cell function. Proc Natl Acad Sci U S A 110:9879-84
Abadi, Yael M; Jeon, Hyungjun; Ohaegbulam, Kim C et al. (2013) Host b7x promotes pulmonary metastasis of breast cancer. J Immunol 190:3806-14
Ghosh, Kaya; Weiss, Louis M (2012) T cell response and persistence of the microsporidia. FEMS Microbiol Rev 36:748-60
Amir, Muhammad; Liu, Kun; Zhao, Enpeng et al. (2012) Distinct functions of JNK and c-Jun in oxidant-induced hepatocyte death. J Cell Biochem 113:3254-65
Park, Sun O; Kumar, Mukesh; Gupta, Sanjeev (2012) TGF-? and iron differently alter HBV replication in human hepatocytes through TGF-?/BMP signaling and cellular microRNA expression. PLoS One 7:e39276
Hofmeyer, Kimberly A; Scandiuzzi, Lisa; Ghosh, Kaya et al. (2012) Tissue-expressed B7x affects the immune response to and outcome of lethal pulmonary infection. J Immunol 189:3054-63
Mukhopadhyay, Aparna; Nieves, Edward; Che, Fa-Yun et al. (2011) Proteomic analysis of endocytic vesicles: Rab1a regulates motility of early endocytic vesicles. J Cell Sci 124:765-75
Scandiuzzi, Lisa; Ghosh, Kaya; Zang, Xingxing (2011) T cell costimulation and coinhibition: genetics and disease. Discov Med 12:119-28

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