The purpose of this training program in endocrinology and metabolism is to provide an opportunity for promising post-doctoral individuals of exceptional quality to train for careers in academic endocrinology and biomedical research. The Program has been supported by this grant mechanism for over 35 years and presents a record among its graduates of superb training and academic achievement. The major features of the Program include intensive research in the laboratory of a participating faculty member and didactic exposure to basic science and clinical investigation. Research areas span a wide range of endocrinological disciplines with centers of excellence in neuroendocrinology, metabolic bone diseases, reproductive endocrinology, diabetes, endocrine genetics, lipoprotein metabolism, molecular endocrinology, and signal transduction. The scientific methods of the faculty include classic endocrinological techniques of basic and clinical investigation as well as the most modern biochemical and molecular studies of hormone action. Expertise in biochemistry, cell biology, molecular biology and physiology are all well-represented by the faculty. Highly experienced clinical investigators provide expertise in a wide variety of sub- specialties with neuroendocrinology, metabolic bone diseases, lipoprotein metabolism and diabetes being particular strengths. Primary facilities are centralized in the Division of Endocrinology in the Department of Medicine. Participating laboratories outside the Division of Endocrinology extend opportunities for endocrinology training to laboratories in the Departments of Physiology and Biophysics, Genetics and Development, Pediatrics, Microbiology, Anatomy and Cell Biology and Pharmacology. Trainees are selected from a very competitive pool of applicants after a thorough review of their credentials and interviews with directors of this Program. The Program focuses upon applicants who hold the M.D. or M.D./Ph.D. degrees and have a strong interest in or prior exposure to investigation.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007271-25
Application #
6634797
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Hyde, James F
Project Start
1977-09-30
Project End
2004-06-30
Budget Start
2003-07-01
Budget End
2004-06-30
Support Year
25
Fiscal Year
2003
Total Cost
$267,740
Indirect Cost
Name
Columbia University (N.Y.)
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Shah, Ankit; Levesque, Kiarra; Pierini, Esmeralda et al. (2018) Effect of sitagliptin on glucose control in type 2 diabetes mellitus after Roux-en-Y gastric bypass surgery. Diabetes Obes Metab 20:1018-1023
Dastagir, Shamael R; Postigo-Fernandez, Jorge; Xu, Chunliang et al. (2017) Efficient Presentation of Multiple Endogenous Epitopes to Both CD4+ and CD8+ Diabetogenic T Cells for Tolerance. Mol Ther Methods Clin Dev 4:27-38
Page-Wilson, Gabrielle; Nguyen, Kim T; Atalayer, Deniz et al. (2017) Evaluation of CSF and plasma biomarkers of brain melanocortin activity in response to caloric restriction in humans. Am J Physiol Endocrinol Metab 312:E19-E26
Nguyen, Kim T; Billington, Charles J; Vella, Adrian et al. (2015) Preserved Insulin Secretory Capacity and Weight Loss Are the Predominant Predictors of Glycemic Control in Patients With Type 2 Diabetes Randomized to Roux-en-Y Gastric Bypass. Diabetes 64:3104-10
Jackness, Clifton; Karmally, Wahida; Febres, Gerardo et al. (2013) Very low-calorie diet mimics the early beneficial effect of Roux-en-Y gastric bypass on insulin sensitivity and ?-cell Function in type 2 diabetic patients. Diabetes 62:3027-32
Messer, Caroline; Boston, Raymond; Leroith, Derek et al. (2012) Pancreatic ?-cell dysfunction in polycystic ovary syndrome: the role of metformin. Endocr Pract 18:685-93
Walker, M D; Babbar, R; Opotowsky, A et al. (2007) Determinants of bone mineral density in Chinese-American women. Osteoporos Int 18:471-8
Walker, M Donovan; Babbar, R; Opotowsky, A R et al. (2006) A referent bone mineral density database for Chinese American women. Osteoporos Int 17:878-87
Donovan, Marcella A; Dempster, David; Zhou, Hua et al. (2005) Low bone formation in premenopausal women with idiopathic osteoporosis. J Clin Endocrinol Metab 90:3331-6
Korner, J; Wardlaw, S L; Liu, S M et al. (2000) Effects of leptin receptor mutation on Agrp gene expression in fed and fasted lean and obese (LA/N-faf) rats. Endocrinology 141:2465-71

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