? Our objective is to train full-time academic investigators. Since modern investigation requires technical expertise, a broad perspective, and facile MD/PhD interactions, MD and PhD Trainees will be educated in concert by faculty representing Departments of Biochemistry, Medicine, Pathology, Pediatrics, Pharmacology, Psychiatry, and the Yerkes Primate Center. Core faculty members offer a wide variety of investigative opportunities, ranging from traditional clinical research to state of the art molecular biology, with extensive interdisciplinary collaborations. Our program includes: a) direct research supervision by individual mentors, b) interactions with other Trainees, Faculty, and Visiting Scientists, c) selected teaching opportunities as preparation for subsequent faculty roles, d) limited clinical experiences as appropriate for both MD and PhD Trainees, and e) a course in Molecular Endocrinology. Each Trainee will be supervised by an experienced mentor with independent research support. A broad education will be based on our Interdepartmental Endocrine Group, including Research Seminars, Journal Club, Clinical Conferences, and Visiting Scientist lectures. MD Trainees will refine subspeciality expertise through limited consultative activities, and PhD Trainees will have selected clinical exposure as a basis for subsequent collaboration with MD investigators. Annual support for four postdoctoral Trainees is requested, reflecting the presence of 13 investigators in the Core Faculty and an additional 19 in the Associate Faculty. Approximately 50 % will be MDs, selected on the basis of scholastic performance and clinical training record (including one prior year of institutionally-supported clinical endocrinology). PhDs will be selected on the basis of graduate performance and promise for independent investigation. The Faculty occupy over 35,000 square feet of laboratory, office and conference room space, on the campuses of Emory University, Grady Memorial Hospital, and the VA Medical Center. Laboratories are fully equipped, office space is available for all Trainees, and libraries are immediately accessible. MD Trainees will be affiliated with Clinical Departments (Psychiatry) or Divisions (Endocrinology), providing excellent opportunities for clinical training and programs of clinical research. Trainees in our program have a strong publication record, and a high percentage have initiated careers in academic investigation ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007298-28
Application #
7269788
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Hyde, James F
Project Start
1978-07-01
Project End
2010-06-30
Budget Start
2007-07-01
Budget End
2008-06-30
Support Year
28
Fiscal Year
2007
Total Cost
$150,421
Indirect Cost
Name
Emory University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
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Han, Jenny E; Alvarez, Jessica A; Jones, Jennifer L et al. (2017) Impact of high-dose vitamin D3 on plasma free 25-hydroxyvitamin D concentrations and antimicrobial peptides in critically ill mechanically ventilated adults. Nutrition 38:102-108
Grassi, Francesco; Tyagi, Abdul Malik; Calvert, John W et al. (2016) Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency. J Bone Miner Res 31:949-63
Alvarez, Jessica A; Ziegler, Thomas R; Millson, Erin C et al. (2016) Body composition and lung function in cystic fibrosis and their association with adiposity and normal-weight obesity. Nutrition 32:447-52
Pacifici, Roberto (2016) T cells, osteoblasts, and osteocytes: interacting lineages key for the bone anabolic and catabolic activities of parathyroid hormone. Ann N Y Acad Sci 1364:11-24
Li, Jau-Yi; Chassaing, Benoit; Tyagi, Abdul Malik et al. (2016) Sex steroid deficiency-associated bone loss is microbiota dependent and prevented by probiotics. J Clin Invest 126:2049-63
Pacifici, Roberto (2016) The Role of IL-17 and TH17 Cells in the Bone Catabolic Activity of PTH. Front Immunol 7:57
Han, Jenny E; Jones, Jennifer L; Tangpricha, Vin et al. (2016) High Dose Vitamin D Administration in Ventilated Intensive Care Unit Patients: A Pilot Double Blind Randomized Controlled Trial. J Clin Transl Endocrinol 4:59-65
Weber, Mary Beth; Ranjani, Harish; Staimez, Lisa R et al. (2016) The Stepwise Approach to Diabetes Prevention: Results From the D-CLIP Randomized Controlled Trial. Diabetes Care 39:1760-7
Kempker, Jordan A; West, Kathryn G; Kempker, Russell R et al. (2015) Vitamin D status and the risk for hospital-acquired infections in critically ill adults: a prospective cohort study. PLoS One 10:e0122136

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