? The University of Michigan Training Program in Gastroenterology provides training for research in gastroenterology to qualified candidates who aspire to an academic career in medicine. Trainees who complete the program are able to compete for external grant funding and function as independent investigators. Our Training Program's recent history demonstrates our success in meeting this goal. The training is focused on a research project under the direct mentorship of a preceptor, in combination with a program of conferences, lectures, and focused courses of study. To capitalize on our environment, time is made available for trainees to participate in the rich educational and collaborative opportunities which the University of Michigan provides. Twenty eight (28) preceptors from eleven (11) separate units with diverse research interests and a wide variety of technical capabilities have a number of ongoing research projects in which a trainee may participate. With time, and in close association with the preceptor, the trainee will develop original research questions to develop independent interests. The research activities covered by the preceptors in the proposal include the broad topics of biochemistry, molecular genetics, cellular biology, biophysics, human and animal physiology, neurobiology, anatomy, outcomes research, epidemiology, clinical pathology, medical diagnostics and therapeutics, all related to gastroenterology. Support is requested for six trainees in the Divisions in adult and pediatric gastroenterology, selected on the basis of their previous academic achievements, potential for research development, and career objectives. M.D. candidates will generally be participating in the GI Division's fellowship program, and Ph.D. applicants will have obtained their degrees in a life science. The efforts of the trainees will be supported by more than 26,000 square feet of research space and $10 million of annual NIH research funding within the GI Division. The combined mass and diversity of resources available for research in gastroenterology, and the demonstrated successes of this program's graduates during the prior funding period provides tangible evidence to support the continuation and expansion of the University of Michigan Training Program in Gastroenterology ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007367-26
Application #
7113237
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Densmore, Christine L
Project Start
1980-09-01
Project End
2010-06-30
Budget Start
2006-07-01
Budget End
2007-06-30
Support Year
26
Fiscal Year
2006
Total Cost
$289,271
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
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Xu, Jingping; Tripathy, Sakya; Rubin, Jonathan M et al. (2012) A new nonlinear parameter in the developed strain-to-applied strain of the soft tissues and its application in ultrasound elasticity imaging. Ultrasound Med Biol 38:511-23
Stidham, Ryan W; Xu, Jingping; Johnson, Laura A et al. (2011) Ultrasound elasticity imaging for detecting intestinal fibrosis and inflammation in rats and humans with Crohn's disease. Gastroenterology 141:819-826.e1
Rubenstein, J H; Nojkov, B; Korsnes, S et al. (2007) Oesophageal hypersensitivity is associated with features of psychiatric disorders and the irritable bowel syndrome. Aliment Pharmacol Ther 26:443-52
Rubenstein, Joel H; Eisen, Glenn M; Inadomi, John M (2004) A cost-utility analysis of secondary prophylaxis for variceal hemorrhage. Am J Gastroenterol 99:1274-88
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Blevins Jr, G T; van de Westerlo, E M; Yule, D I et al. (1994) Characterization of cholecystokininA receptor agonist activity by a family of cholecystokininB receptor antagonists. J Pharmacol Exp Ther 269:911-6
Blevins Jr, G T; van de Westerlo, E M; Williams, J A (1994) Nucleoside diphosphate kinase associated with rat pancreatic membranes regulates CCK receptor affinity. Am J Physiol 267:G866-74
Wishart, M J; Andrews, P C; Nichols, R et al. (1993) Identification and cloning of GP-3 from rat pancreatic acinar zymogen granules as a glycosylated membrane-associated lipase. J Biol Chem 268:10303-11
Blevins Jr, G T; Williams, J A (1992) ATP induces two cholecystokinin binding affinity states in permeabilized rat pancreatic acini. Am J Physiol 263:G44-51

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