This renewal application for the Harvard Medical School Fellowship in Pediatric Gastroenterology and Nutrition combines two T32 awards currently active at Children's and Massachusetts General Hospitals, Boston. The overall goal of the program is to prepare pediatric physician-scientists or non-physician scientists for academic careers in independent research on topics relevant to digestive diseases in infancy, childhood, and adult life. We offer two research training tracks focused on the biology and diseases of the intestine: one in basic or disease-oriented research, and the other in clinical or patient-oriented research. The Disease-Oriented research training track focuses on 1) epithelial cell and developmental biology, 2) innate and acquired mucosal immunology, and 3) epithelial-microbial interactions. The Patient-Oriented research training track focuses on 1) intestinal and nutritional epidemiology, 2) outcomes research, and 3) clinical trials. The program provides an in depth comprehensive scientific experience for each trainee in a research group at the forefront of its field. Ten postdoctoral positions are requested for two years of research training (2 or 3/yr in basic and 2 or 3/yr in clinical research training). Forty outstanding faculty support this effort. Training faculty are drawn from all Harvard Affiliated Hospitals and Research Institutes, the Harvard Medical School, and the Harvard School of Public Health. Opportunities for cross fertilization are abundant. The Program Director is Dr. Wayne I. Lencer, Associate Professor of Pediatrics, Harvard Medical School, a widely respected investigator and mentor. A Career Development Committee is assembled for each trainee to provide mentoring in scientific and career development. Didactic course work is required for both basic and clinical research training tracks and supplemented with relevant seminars and journal clubs, a course in the responsible conduct of research, and a bi-annual research retreat. Trainees in clinical research must obtain a Master's Degree in Medical Science or Public Heath (MMSc or MPH), both from the Harvard School of Public Health. Integration of training with the candidates' future goals in academic medicine, a strong focus on original research, and career development are essential features of the program.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007477-25
Application #
7326846
Study Section
Special Emphasis Panel (ZDK1-GRB-4 (O2))
Program Officer
Densmore, Christine L
Project Start
1983-12-01
Project End
2008-11-30
Budget Start
2007-12-01
Budget End
2008-11-30
Support Year
25
Fiscal Year
2008
Total Cost
$540,250
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
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Mahoney, Lisa; Rosen, Rachel (2017) Feeding Problems and Their Underlying Mechanisms in the Esophageal Atresia-Tracheoesophageal Fistula Patient. Front Pediatr 5:127
Mahoney, Lisa B; Nurko, Samuel; Rosen, Rachel (2017) The Prevalence of Rome IV Nonerosive Esophageal Phenotypes in Children. J Pediatr 189:86-91

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