EXCEED THE SPACE PROVIDED. This training program, which has been in continuous existence since 1975,is designed to prepare physicians and selected postdoctoral scientists from allied fields for academic careers as independently funded investigators on the faculty of university-based medical centers in either basic or clinical research related to digestive diseases. This training program is closely integrated into the categorical Gastroenterology fellowship program at Brigham & Women's Hospital which has two related tracks that reflect the major goals of the Institutional National Research Service Award (NRSA). These are a basic research track (3 trainees/year) and a clinical research track (1 trainee/year), both of which include a categorical year of clinical fellowship training in Gastroenterology funded by the institution and two years01 research training supported by the Institutional NRSA for the development of physician-scientists and clinical investigators, respectively. Emphasis is placed on the recruitment of trainees with prior research experience (e.g. M.D.: Ph.D. degrees). Both tracks continuously take advantage of the faculty and expertise of the Harvard Medical School and its affiliated institutions (Dana Farber Cancer Institute, Harvard School of Public Health, Harvard Institutes of Medicine and Boston Veterans Administration Health Care System) and programs (Harvard Digestive Diseases Center) with which the Brigham & Women's Hospital Gastroenterology Division in the Thorn Medical Research Building, the primary training site, is closely aligned. The Program Director, Dr. Richard S. Blumberg and 19 current preceptors provide training in the following major areas related to digestive diseases research: 1) Immunologyand Virology (Drs R. Blumberg, M. Koziel, S. Balk, S. Colgan, C. Terhorst); 2) Genetics (Drs. R. Hershberg, D. Beier, R. Maas, B. Paigen A. Pardee); 3) Cell and Molecular Physiology (Drs. M. Carey, A. Dutta, R. Goyal, B. Lowell, C. Serhan, D. Soybel) and; 4) Clinical Research and Epidemiology (Drs. F. Li, G. Colditz, S. Syngal, N. Grace). The program is administerec by an Executive Committee that is composed of individuals whose interests reflect these areas (Drs. R. Blumberj [Immunology], M. Carey [Cell and Molecular Physiology], R. Hershberg [Genetics], F. Li [Clinical Research anc Epidemiology] and J. Trier emeritus member) and which provides oversight for the recruitment, training and careei development of trainees. The program provides support for coursework in basic science disciplines from the Harvan Medical School and formal training in public health and epidemiology through a Masters in Public Health degree fron the Harvard School of PtiblicHealth PERFORMANCE SITE ========================================Section End===========================================

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007533-20
Application #
6836106
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Densmore, Christine L
Project Start
1985-07-01
Project End
2006-08-31
Budget Start
2005-01-01
Budget End
2006-08-31
Support Year
20
Fiscal Year
2005
Total Cost
$299,158
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Jirapinyo, Pichamol; Thompson, Andrew C; Kröner, Paul T et al. (2018) Metabolic Effect of Foregut Exclusion Demonstrated by the Impact of Gastrogastric Fistula on Recurrence of Diabetes. J Am Coll Surg 226:259-266.e1
Schulman, Allison R; Kumar, Nitin; Thompson, Christopher C (2018) Transoral outlet reduction: a comparison of purse-string with interrupted stitch technique. Gastrointest Endosc 87:1222-1228
Schulman, Allison R; Thompson, Christopher C (2018) Endoscopic reconstruction of Roux-en-Y gastric bypass with placement of gastrojejunal and remnant-jejunal lumen-apposing metal stents. Gastrointest Endosc 87:890-891
Kumar, Nitin; Abu Dayyeh, Barham K; Lopez-Nava Breviere, Gontrand et al. (2018) Endoscopic sutured gastroplasty: procedure evolution from first-in-man cases through current technique. Surg Endosc 32:2159-2164
Jin, David X; Lacson, Ronilda; Cochon, Laila R et al. (2018) A Clinical Model for the Early Diagnosis of Acute Pancreatitis in the Emergency Department. Pancreas 47:871-879
Kim, Walter M; Kaser, Arthur; Blumberg, Richard S (2017) A role for oncostatin M in inflammatory bowel disease. Nat Med 23:535-536
Jirapinyo, Pichamol; Thompson, Christopher C (2017) Endoscopic Bariatric and Metabolic Therapies: Surgical Analogues and Mechanisms of Action. Clin Gastroenterol Hepatol 15:619-630
Schulman, Allison R; Ryou, Marvin; Aihara, Hiro et al. (2017) EUS-guided intrahepatic portosystemic shunt with direct portal pressure measurements: a novel alternative to transjugular intrahepatic portosystemic shunting. Gastrointest Endosc 85:243-247
Kumar, Nitin; Thompson, Christopher C (2017) Remnant gastropathy due to bile reflux after Roux-en-Y gastric bypass: a unique cause of abdominal pain and successful treatment with ursodiol. Surg Endosc 31:5399-5402
Barnes, Edward L; Nestor, Molly; Onyewadume, Louisa et al. (2017) High Dietary Intake of Specific Fatty Acids Increases Risk of Flares in Patients With Ulcerative Colitis in Remission During Treatment With Aminosalicylates. Clin Gastroenterol Hepatol 15:1390-1396.e1

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