Continuation of an institutional training program in Cellular Physiology is proposed for postdoctoral fellows from the Basic Health Sciences or subsequent to residency programs in Nephrology, Anesthesiology, Pulmonary Medicine, or Internal Medicine. The goal is to train potential academic investigators in cell membrane physiology, biochemistry, and molecular biology. Basic laboratory training requires a full-time commitment of 2-3 years under the guidance of an established scientist with training directed at the utilization and application of modern electrophysiological, biochemical, and cell and molecular biological tools to problems relating to epithelial transport, ion channels, growth and differentiation, and various pathophysiological states such as cystic fibrosis and renal failure. All participating faculty have their primary or secondary appointments in Physiology and Biophysics. The intimate relationship between the mentor and the trainee will foster a thorough understanding of the scientific method, informal seminars and discussions of planned experiments and current results are important components of the program. All preceptors have a clear commitment to training new investigators and possess ample laboratory space and external funding for training. Trainees will be expected to master at least one major investigative technique, complete at least one major research project, and present their work at a national meeting. Emphasis will be placed upon developing critically thinking scientists who are well-versed in the potential uses, advantages, and disadvantages of each technique. The existence of over 70 separate research centers (such as the Comprehensive Cancer Center, the Center for AIDS Research, the Nuclear Imaging Research Center, and the Center for Biophysical Sciences and Technology) on the UAB campus amplify the academic and research opportunities, creating an excellent environment for this training program. Fellows completing the program will be competitive candidates for academic research careers.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007545-17
Application #
6710023
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Rankin, Tracy L
Project Start
1987-07-01
Project End
2008-02-28
Budget Start
2004-03-01
Budget End
2005-02-28
Support Year
17
Fiscal Year
2004
Total Cost
$135,959
Indirect Cost
Name
University of Alabama Birmingham
Department
Physiology
Type
Schools of Medicine
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Farrington, Crystal A; Robbin, Michelle L; Lee, Timmy et al. (2018) Postoperative Ultrasound, Unassisted Maturation, and Subsequent Primary Patency of Arteriovenous Fistulas. Clin J Am Soc Nephrol 13:1364-1372
Mustian, Margaux N; Shelton, Brittany A; MacLennan, Paul A et al. (2018) Ethnic and Age Disparities in Outcomes among Liver Transplant Waitlist Candidates. Transplantation :
Martins, Paulo N; Mustian, Margaux N; MacLennan, Paul A et al. (2018) Impact of the new kidney allocation system A2/A2B ? B policy on access to transplantation among minority candidates. Am J Transplant 18:1947-1953
Mustian, Margaux N; Cannon, Robert M; MacLennan, Paul A et al. (2018) Landscape of ABO-Incompatible Live Donor Kidney Transplantation in the US. J Am Coll Surg 226:615-621
Yanik, Megan V; Irvin, Marguerite R; Beasley, T Mark et al. (2017) Influence of Kidney Transplant Status on Warfarin Dose, Anticoagulation Control, and Risk of Hemorrhage. Pharmacotherapy 37:1366-1373
De Miguel, Carmen; Hamrick, William C; Hobbs, Janet L et al. (2017) Endothelin receptor-specific control of endoplasmic reticulum stress and apoptosis in the kidney. Sci Rep 7:43152
Boddu, Ravindra; Fan, Chunlan; Rangarajan, Sunil et al. (2017) Unique sex- and age-dependent effects in protective pathways in acute kidney injury. Am J Physiol Renal Physiol 313:F740-F755
Saha, Manish; Allon, Michael (2017) Diagnosis, Treatment, and Prevention of Hemodialysis Emergencies. Clin J Am Soc Nephrol 12:357-369
Saha, M; McDaniel, J K; Zheng, X L (2017) Thrombotic thrombocytopenic purpura: pathogenesis, diagnosis and potential novel therapeutics. J Thromb Haemost 15:1889-1900
Al-Balas, Alian; Lee, Timmy; Young, Carlton J et al. (2017) The Clinical and Economic Effect of Vascular Access Selection in Patients Initiating Hemodialysis with a Catheter. J Am Soc Nephrol 28:3679-3687

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