This application is a request for continued support for urological research training at the Johns Hopkins University School of Medicine. The Program Director asserts that there exists a shortage of trained urological research scientists and that this program addresses a critical national need. This application addresses training of urological scientists at several levels including candidates who have completed a urological residency (M.D. candidate), the postdoctoral Ph.D., and the M.D. urological research fellow who wishes research training during residency. Predoctoral Ph.D. students are not supported by this application. The program is diverse in the levels of investigators which it seeks to attract.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007552-15
Application #
6380279
Study Section
Special Emphasis Panel (SRC)
Program Officer
Bishop, Terry Rogers
Project Start
1987-05-01
Project End
2002-04-30
Budget Start
2001-05-01
Budget End
2002-04-30
Support Year
15
Fiscal Year
2001
Total Cost
$205,185
Indirect Cost
Name
Johns Hopkins University
Department
Urology
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Hurley, Paula J; Sundi, Debasish; Shinder, Brian et al. (2016) Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer. Clin Cancer Res 22:448-58
Sundi, Debasish; Faisal, Farzana A; Trock, Bruce J et al. (2015) Reclassification rates are higher among African American men than Caucasians on active surveillance. Urology 85:155-60
Vander Griend, Donald J; Litvinov, Ivan V; Isaacs, John T (2014) Conversion of androgen receptor signaling from a growth suppressor in normal prostate epithelial cells to an oncogene in prostate cancer cells involves a gain of function in c-Myc regulation. Int J Biol Sci 10:627-42
Sundi, D; Wang, V M; Pierorazio, P M et al. (2014) Very-high-risk localized prostate cancer: definition and outcomes. Prostate Cancer Prostatic Dis 17:57-63
Sundi, Debasish; Kryvenko, Oleksandr N; Carter, H Ballentine et al. (2014) Pathological examination of radical prostatectomy specimens in men with very low risk disease at biopsy reveals distinct zonal distribution of cancer in black American men. J Urol 191:60-7
Ross, A E; Feng, F Y; Ghadessi, M et al. (2014) A genomic classifier predicting metastatic disease progression in men with biochemical recurrence after prostatectomy. Prostate Cancer Prostatic Dis 17:64-9
Sundi, Debasish; Wang, Vinson; Pierorazio, Phillip M et al. (2014) Identification of men with the highest risk of early disease recurrence after radical prostatectomy. Prostate 74:628-36
Sundi, Debasish; Ross, Ashley E; Humphreys, Elizabeth B et al. (2013) African American men with very low-risk prostate cancer exhibit adverse oncologic outcomes after radical prostatectomy: should active surveillance still be an option for them? J Clin Oncol 31:2991-7
Anusionwu, Ifeanyichukwu I; Wright, E James (2013) Indications for revision of artificial urinary sphincter and modifiable risk factors for device-related morbidity. Neurourol Urodyn 32:63-5
Suson, Kristina D; Sponseller, Paul D; Gearhart, John P (2013) Bony abnormalities in classic bladder exstrophy: the urologist's perspective. J Pediatr Urol 9:112-22

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