This application is a request for continued support for urological research training at the Johns Hopkins University School of Medicine. The Program Director asserts that there exists a shortage of trained urological research scientists and that this program addresses a critical national need. This application addresses training of urological scientists at several levels including candidates who have completed a urological residency (M.D. candidate), the postdoctoral Ph.D., and the M.D. urological research fellow who wishes research training during residency. Predoctoral Ph.D. students are not supported by this application. The program is diverse in the levels of investigators which it seeks to attract.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (SRC)
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Bishop, Terry Rogers
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Johns Hopkins University
Schools of Medicine
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Hurley, Paula J; Sundi, Debasish; Shinder, Brian et al. (2016) Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer. Clin Cancer Res 22:448-58
Sundi, Debasish; Faisal, Farzana A; Trock, Bruce J et al. (2015) Reclassification rates are higher among African American men than Caucasians on active surveillance. Urology 85:155-60
Vander Griend, Donald J; Litvinov, Ivan V; Isaacs, John T (2014) Conversion of androgen receptor signaling from a growth suppressor in normal prostate epithelial cells to an oncogene in prostate cancer cells involves a gain of function in c-Myc regulation. Int J Biol Sci 10:627-42
Sundi, D; Wang, V M; Pierorazio, P M et al. (2014) Very-high-risk localized prostate cancer: definition and outcomes. Prostate Cancer Prostatic Dis 17:57-63
Sundi, Debasish; Kryvenko, Oleksandr N; Carter, H Ballentine et al. (2014) Pathological examination of radical prostatectomy specimens in men with very low risk disease at biopsy reveals distinct zonal distribution of cancer in black American men. J Urol 191:60-7
Ross, A E; Feng, F Y; Ghadessi, M et al. (2014) A genomic classifier predicting metastatic disease progression in men with biochemical recurrence after prostatectomy. Prostate Cancer Prostatic Dis 17:64-9
Sundi, Debasish; Wang, Vinson; Pierorazio, Phillip M et al. (2014) Identification of men with the highest risk of early disease recurrence after radical prostatectomy. Prostate 74:628-36
Anusionwu, Ifeanyi; Tekes, Aylin; Stec, Andrew A et al. (2013) Comparison of musculoskeletal anatomic relationships, determined by magnetic resonance imaging, in postpubertal female patients with and without classic bladder exstrophy. BJU Int 112:E195-200
Sundi, Debasish; Ross, Ashley E; Humphreys, Elizabeth B et al. (2013) African American men with very low-risk prostate cancer exhibit adverse oncologic outcomes after radical prostatectomy: should active surveillance still be an option for them? J Clin Oncol 31:2991-7
Anusionwu, Ifeanyichukwu I; Wright, E James (2013) Indications for revision of artificial urinary sphincter and modifiable risk factors for device-related morbidity. Neurourol Urodyn 32:63-5

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