Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007680-05
Application #
2135301
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1991-09-20
Project End
1996-06-30
Budget Start
1995-09-01
Budget End
1996-06-30
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Type
Organized Research Units
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
Horikoshi, Momoko; Day, Felix R; Akiyama, Masato et al. (2018) Elucidating the genetic architecture of reproductive ageing in the Japanese population. Nat Commun 9:1977
Toro, Carlos A; Wright, Hollis; Aylwin, Carlos F et al. (2018) Trithorax dependent changes in chromatin landscape at enhancer and promoter regions drive female puberty. Nat Commun 9:57
Mighell, Taylor L; Evans-Dutson, Sara; O'Roak, Brian J (2018) A Saturation Mutagenesis Approach to Understanding PTEN Lipid Phosphatase Activity and Genotype-Phenotype Relationships. Am J Hum Genet 102:943-955
Yoder, Nate; Gouaux, Eric (2018) Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography. PLoS One 13:e0202134
Toro, C A; Aylwin, C F; Lomniczi, A (2018) Hypothalamic epigenetics driving female puberty. J Neuroendocrinol 30:e12589
Yoder, Nate; Yoshioka, Craig; Gouaux, Eric (2018) Gating mechanisms of acid-sensing ion channels. Nature 555:397-401
Meinig, J Matthew; Ferrara, Skylar J; Banerji, Tania et al. (2017) Targeting Fatty-Acid Amide Hydrolase with Prodrugs for CNS-Selective Therapy. ACS Chem Neurosci 8:2468-2476
Ferrara, Skylar J; Meinig, J Matthew; Placzek, Andrew T et al. (2017) Ester-to-amide rearrangement of ethanolamine-derived prodrugs of sobetirome with increased blood-brain barrier penetration. Bioorg Med Chem 25:2743-2753
Placzek, Andrew T; Ferrara, Skylar J; Hartley, Meredith D et al. (2016) Sobetirome prodrug esters with enhanced blood-brain barrier permeability. Bioorg Med Chem 24:5842-5854
Toro, Cecilia; Trapani, Josef G; Pacentine, Itallia et al. (2015) Dopamine Modulates the Activity of Sensory Hair Cells. J Neurosci 35:16494-503

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