The Renal Epidemiology Training Program prepares trainees to design, conduct, and analyze independent research in the expansive field of kidney disease in collaboration with faculty in the UNC Kidney Center (UNCKC), the Department of Epidemiology and other UNC schools and departments. The UNCKC, whose director Dr. Ronald Falk reports directly to the CEO and Dean of the UNC Healthcare System, allows for an integrated approach to research and education. The UNCKC includes members in the Schools of Medicine, Public Health, Dentistry, Pharmacology, and the College of Arts and Sciences. In this over-arching structure, trainees have the opportunity to obtain their Masters of Public Health (MPH), PhD, or design and implement other structured training. Guidance is provided by mentoring teams comprised of faculty with expertise and established collaborative research interests across diverse areas of current interest in the realm of kidney research including epidemiology, immunology, genetics, pathology, pharmacology, health policy and more. Faculty have special expertise in systemic diseases that affect the kidney, including lupus, vasculitis, diabetes, and hypertension. Access to study populations is available through clinics and existing study databases, such as the Atherosclerosis Risk in Communities (ARIC) study and the Strong Heart Study. The academic curriculum is supplemented by a structured schedule of seminars, conferences, performance reviews and close interaction with faculty. Trainees are well-informed about the scope and impact of areas of research needed in the field of kidney disease, and work with faculty mentoring teams to review the literature, develop research initiatives, conduct and analyze data, and prepare abstracts, research presentations, manuscripts and grants. This program began in 1998 with one post-doctoral trainee and has expanded to three post-doctoral (one minority supplement for 2006-2008) and two pre-doctoral candidates. The post doctoral program includes both adult and pediatric trainees. Eight of 9 post-doctoral trainees and all 3 pre-doctoral candidates have degrees from prestigious U.S. universities. One of the post-doctoral and 2/3 of our pre-doctoral trainees are from underrepresented minorities. Six candidates have completed their training, with five now in faculty positions at excellent academic medical centers and one in industry. All trainees have published manuscripts or manuscripts underway for a total of 103 manuscripts.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZDK1-GRB-S (J3))
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Rys-Sikora, Krystyna E
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University of North Carolina Chapel Hill
Internal Medicine/Medicine
Schools of Medicine
Chapel Hill
United States
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Kahkoska, Anna R; Isom, Scott; Divers, Jasmin et al. (2018) The early natural history of albuminuria in young adults with youth-onset type 1 and type 2 diabetes. J Diabetes Complications 32:1160-1168
Hardy, Shakia T; Zeng, Donglin; Kshirsagar, Abhijit V et al. (2018) Primary prevention of chronic kidney disease through population-based strategies for blood pressure control: The ARIC study. J Clin Hypertens (Greenwich) 20:1018-1026
Kahkoska, Anna R; Watts, Madison E; Driscoll, Kimberly A et al. (2018) Understanding antagonism and synergism: A qualitative assessment of weight management in youth with Type 1 diabetes mellitus. Obes Med 9:21-31
Li, Xiaojuan; Cole, Stephen R; Westreich, Daniel et al. (2018) Primary non-adherence and the new-user design. Pharmacoepidemiol Drug Saf 27:361-364
Allard, Denise E; Wang, Yan; Li, Jian Joel et al. (2018) Schwann cell-derived periostin promotes autoimmune peripheral polyneuropathy via macrophage recruitment. J Clin Invest 128:4727-4741
Mahoney, Shannon L; Nachman, Patrick H (2018) Persistent Hematuria in ANCA Vasculitis: Ominous or Innocuous? Clin J Am Soc Nephrol 13:201-202
Brown, Landon C; Jobson, Meghan A; Payan Schober, Fernanda et al. (2017) The Evolving Role of Rituximab in Adult Minimal Change Glomerulopathy. Am J Nephrol 45:365-372
Li, Xiaojuan; Kshirsagar, Abhijit V; Brookhart, M Alan (2017) Safety of intravenous iron in hemodialysis patients. Hemodial Int 21 Suppl 1:S93-S103
Jones, Britta E; Yang, Jiajin; Muthigi, Akhil et al. (2017) Gene-Specific DNA Methylation Changes Predict Remission in Patients with ANCA-Associated Vasculitis. J Am Soc Nephrol 28:1175-1187
Zhong, Victor W; Crandell, Jamie L; Shay, Christina M et al. (2017) Dietary intake and risk of non-severe hypoglycemia in adolescents with type 1 diabetes. J Diabetes Complications 31:1340-1347

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