Disorders of endocrinology and metabolism are prevalent in the U.S. Addressing these difficult dilemmas requires not only the development of a critical mass of physicians to care for affected patients, but also the training of skilled researchers to develop innovative therapies and preventive measures and to delve into the basic mechanisms of diseases. The Indiana University School of Medicine is a leader in many fields of medicine. Its Section of Pediatric Endocrinology and the Division of Endocrinology and Metabolism in the Department of Medicine are both large well respected research divisions with long histories of mentoring pre-and postdoctoral trainees, including training one another's fellows in research that spans the spectrum of pediatric and adult Endocrinology. The Endocrine Scientist Training Program described here provides the opportunity for young scientists in Pediatric, Adult, or Combined Medicine-Pediatric Endocrinology training to enhance their skills in either basic laboratory, clinical, or translational research, leading to careers as independent academic researchers. After completion of their residency training, highly qualified physicians enter either the Internal Medicine, Pediatric Endocrinology, or combined Medicine- Pediatric Endocrinology fellowship, receive clinical training in the respective discipline[s), then enter this combined program in one of two tracks, the Basic Science of Endocrinology Track or the Endocrinology Clinical Research Track. These tracks provide extensive direct and didactic research training. The Basic Science of Endocrinology Track requires a series of graduate level courses, including studies in Molecular Biology, Biostatistics, and Research Ethics. The Endocrinology Clinical Research Track trainees obtain a Masters of Science in Clinical Research through our K30-funded CITE program. Trainees in the Endocrine Scientist Training Program receive two years of support for their training. Over the previous project period, this program has trained five top-notch physician scientists in the field of Endocrinology. The graduates of this program all have academic positions at major medical schools, and we anticipate that they will continu to engage in cutting-edge research to make major contributions to the health of the American people.

Public Health Relevance

The eruption of type 2 diabetes and related endocrine and metabolic problems is taking a tremendous public health toll. The elucidation of disease mechanisms and the development of new treatments for these and related conditions is critical to address these issues. This can only be done by training a critical mass of young researchers to develop and carry forward the efforts to solve these problems.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK065549-10
Application #
8728810
Study Section
Special Emphasis Panel (ZDK1-GRB-W (J3))
Program Officer
Castle, Arthur
Project Start
2004-01-01
Project End
2015-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
10
Fiscal Year
2014
Total Cost
$139,170
Indirect Cost
$14,072
Name
Indiana University-Purdue University at Indianapolis
Department
Pediatrics
Type
Schools of Medicine
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Chen, Melinda E; Chandramouli, Aaditya G; Considine, Robert V et al. (2018) Comparison of ?-Cell Function Between Overweight/Obese Adults and Adolescents Across the Spectrum of Glycemia. Diabetes Care 41:318-325
Hannon, Tamara S; Watson, Sara E; Jalou, Hasnaa E et al. (2018) Characteristics of Obstructive Sleep Apnea Across the Spectrum of Glucose Tolerance in Obese Adolescents. Front Endocrinol (Lausanne) 9:281
Hansen, David W; Nebesio, Todd D; DiMeglio, Linda A et al. (2018) Prevalence of Nephrocalcinosis in Pseudohypoparathyroidism: Is Screening Necessary? J Pediatr 199:263-266
Schoelwer, Melissa J; Donahue, Kelly L; Didrick, Paula et al. (2017) One-Year Follow-Up of Girls with Precocious Puberty and Their Mothers: Do Psychological Assessments Change over Time or with Treatment? Horm Res Paediatr 88:347-353
Chen, Melinda; Lash, Matthew; Nebesio, Todd et al. (2017) Change in BMI after radioactive iodine ablation for graves disease. Int J Pediatr Endocrinol 2017:5
Schoelwer, Melissa J; Tu, Wanzhu; Zhou, Junyi et al. (2017) TARGETED LEVOTHYROXINE THERAPY FOR TREATMENT OF CONGENITAL HYPOTHYROIDISM. Endocr Pract 23:1067-1071
Folsom, Lisal J; Slaven, James E; Nabhan, Zeina M et al. (2017) CHARACTERIZATION OF SPONTANEOUS AND INDUCED PUBERTY IN GIRLS WITH TURNER SYNDROME. Endocr Pract 23:768-774
Neyman, Anna; Eugster, Erica A (2017) Treatment of Girls and Boys with McCune-Albright Syndrome with Precocious Puberty - Update 2017. Pediatr Endocrinol Rev 15:136-141
Schoelwer, Melissa J; Viswanathan, Vidhya; Wilson, Amy et al. (2017) Infants With Congenital Adrenal Hyperplasia Are at Risk for Hypercalcemia, Hypercalciuria, and Nephrocalcinosis. J Endocr Soc 1:1160-1167
Folsom, Lisal J; Hannon, Tamara S (2017) Collaboration Is Key for Successful Treatment of Youth-Onset Type 2 Diabetes. J Adolesc Health 60:360-362

Showing the most recent 10 out of 55 publications