Training in epidemiology and outcomes research is essential to prepare the next generation of researchers in a rapidly moving field. Discoveries in genetics, pathophysiology, diagnosis, and treatment of several Gl and liver disorders have been made at a very rapid pace over the past few years. Modern clinical and translational researchers need to be equipped with extensive training in the methods and conduct of research in areas that are becoming highly sophisticated and specialized;these include conventional epidemiology, clinical epidemiology and outcomes, genetic and molecular epidemiology, and health services research. These areas address the need for translational research both from bench to bedside as well as from bedside to clinical practice. The proposed training program has three objectives: (1) To produce physician scientists who are thoroughly trained in the content areas, methods, and ethics critical for epidemiology and outcomes research in gastroenterology and hepatology; (2) To produce physician scientists who have mastered basic research skills, including project design, planning, funding, execution, management, and reporting;and (3) To produce physician scientists who will pursue a research agenda that will new discoveries as well as make the best use of current discoveries to make the health care safer, more effective, more patient-centered, more timely, more efficient, and more equitable. The program will take advantage of outstanding expertise in research and mentoring in epidemiology and outcomes research available at Baylor College of Medicine and UT-School of Public Health including the Gl and Liver Section and the Houston Center for Quality of Care and Utilization Studies (HCQCUS). The proposed fellowship training program has four elements: 1) vigorous mentoring for each individual fellow in a self-selected area of concentration to engender the development of a feasible career research agenda that has potential for substantial impact, and 2) formal research training resulting in a master's degree to provide a foundation of research skills, 3) Applied research seminars to model use of research skills and provide a foundation in health services research knowledge and skills, and 4) participation in the research process as a co- investigator and as a principle investigator to provoke application of research skills.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Institutional National Research Service Award (T32)
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Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Densmore, Christine L
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Baylor College of Medicine
Internal Medicine/Medicine
Schools of Medicine
United States
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Kramer, J R; Puenpatom, A; Erickson, K F et al. (2018) Real-world effectiveness of elbasvir/grazoprevir In HCV-infected patients in the US veterans affairs healthcare system. J Viral Hepat 25:1270-1279
Kramer, J R; El-Serag, H B; Taylor, T J et al. (2017) Hepatitis C virus-related complications are increasing in women veterans: A national cohort study. J Viral Hepat 24:955-965
Tansel, Aylin; Katz, Lior H; El-Serag, Hashem B et al. (2017) Incidence and Determinants of Hepatocellular Carcinoma in Autoimmune Hepatitis: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol 15:1207-1217.e4
El-Serag, Hashem B; Kanwal, Fasiha; Richardson, Peter et al. (2016) Risk of hepatocellular carcinoma after sustained virological response in Veterans with hepatitis C virus infection. Hepatology 64:130-7
Khan, Anam; Tansel, Aylin; White, Donna L et al. (2016) Efficacy of Psychosocial Interventions in Inducing and Maintaining Alcohol Abstinence in Patients With Chronic Liver Disease: A Systematic Review. Clin Gastroenterol Hepatol 14:191-202.e1-4; quiz e20
Shah, Rajesh; Abraham, Bincy; Hou, Jason et al. (2015) Frequency and associated factors of hair loss among patients with inflammatory bowel disease. World J Gastroenterol 21:229-32
Thrift, Aaron P; Kramer, Jennifer R; Alsarraj, Abeer et al. (2014) Fat mass by bioelectrical impedance analysis is not associated with increased risk of Barrett esophagus. J Clin Gastroenterol 48:218-23
Fischbach, Lori A; Graham, David Y; Kramer, Jennifer R et al. (2014) Association between Helicobacter pylori and Barrett's esophagus: a case-control study. Am J Gastroenterol 109:357-68
Kruse, Robert L; Kramer, Jennifer R; Tyson, Gia L et al. (2014) Clinical outcomes of hepatitis B virus coinfection in a United States cohort of hepatitis C virus-infected patients. Hepatology 60:1871-8
Khandwalla, Hashim E; Graham, David Y; Kramer, Jennifer R et al. (2014) Barrett's esophagus suspected at endoscopy but no specialized intestinal metaplasia on biopsy, what's next? Am J Gastroenterol 109:178-82

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