Diabetes is a global heath epidemic affecting close to 400M people worldwide. Even with rigorous management increased risk for diabetic complications remains. Bioengineering approaches are providing innovate technologies that are increasingly overcoming the current limitations in developing new diagnostics, treatments and cures for diabetes and complications. However there is a shortage of a skilled scientific workforce able to work on these developments. The University of Colorado is uniquely placed to develop an innovative new program to train future scientists with the skills and knowledge to solve existing and future problems in diabetes research and clinical care. This includes world-renowned research and clinical programs in diabetes, particularly type1 diabetes; exceptional engineering research and training programs; and bioengineering research and training that is fully integrated with the Medical campus. To maintain the strong and growing areas of cooperation intersecting bioengineering and diabetes research we propose an innovative new training program: Bioengineering Interdisciplinary Training for Diabetes Research. The primary goals of this program are: 1). To attract high-quality trainees with engineering/quantitative backgrounds; 2). To provide in-depth, multi-disciplinary research training for predoctoral trainees integrating bioengineering and diabetes; and 3). To prepare trainees for transition to individual fellowships and research careers in academia or industry. To effectively achieve these goals, our research training will follow 3 core principles: a). That a successful bioengineering career requires an intrinsically multi-disciplinary approach, with scientists equipped with skills covering a broad variety of fields; b). That successful training of these scientists will require constant interactions between trainees and cross- disciplinary mentors at all levels of research; and c). That developing such scientists requires an institutional environment with breadth and depth, established interactions between engineering and clinical science, and faculty committed to this training. Our innovative research training program will combine didactic and hands on coursework, lab-based research, clinical experiences and career skills. Research areas will focus on true strengths at the institution in which established interactions between bioengineering and diabetes are present, including designing biomarkers and therapeutic interventions for diabetes and complication, clinical trials, imaging diagnostics for diabetes and complications, biomaterials and cell-based therapies, and artificial pancreas diabetes management. Our current outcomes achieved in bioengineering training, including for under-represented populations; the depth of expertise in diabetes and engineering research; the significant institutional support, and the wide range of facilities available make a compelling argument to develop such a program at the University of Colorado.

Public Health Relevance

Diabetes is a global heath epidemic, and bioengineering approaches and new technology are needed to advance the development of effective diagnostics, management strategies and cures for diabetes. However there is a shortage of a skilled scientific workforce able to work on these developments, due to the unique training required. We will leverage the outstanding previous experience, expertise, resources and institutional support at the University of Colorado to develop such a training program, in order to attract and train outstanding PhD students, to prepare them for outstanding research careers in academia and industry.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
1T32DK120520-01A1
Application #
9934855
Study Section
Kidney, Urologic and Hematologic Diseases D Subcommittee (DDK)
Program Officer
Castle, Arthur
Project Start
2020-07-01
Project End
2025-06-30
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
1
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Engineering (All Types)
Type
Biomed Engr/Col Engr/Engr Sta
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045