The University of Pittsburgh seeks continued support for our multidisciplinary and innovative pre-doctoral training program in Cellular Approaches to Tissue Engineering and Regeneration (CATER). The CATER training program combines faculty and research expertise from a multitude of disciplines that combine tissue engineering with molecular and cellular approaches of therapies for human disease and regeneration. Tissue engineering and regenerative medicine are two interdisciplinary fields that are inseparably coupled, bringing together scientists from human biology, engineering, medicine and applied technologies to focus on the repair and replacement of human tissues. One of the most significant challenges in regenerative medicine is developing the next generation of experts in each of the enabling disciplines that must be trained cognizant of the crossdisciplinary challenges and approaches required to solve tissue engineering problems. To address this issue we developed the CATER pre-doctoral training program to fill the gaps that often exist in more traditional departmentally-focused research training programs. The goal of the CATER training program is to provide a solid foundation upon which to build a productive and independent career in cellular and tissue based therapy for human disease and injury. This goal is accomplished via a highly coordinated and mentored interdisciplinary training program with a combination of required and elective courses, research activities and specialized training opportunities. Our short history (first 5-years of funding support) provides evidence that we are accomplishing these training objectives. The CATER training program, combining diverse training faculty and coursework in tissue engineering and cellular and molecular biology of disease and therapy, provides a rich educational experience and more numerous training opportunities for students than obtained in more traditional or individual university departments or programs. The CATER training program provides students the training and expertise we believe is necessary to succeed in the rapidly evolving and highly interdisciplinary fields of cellular and tissue based engineering. The University of Pittsburgh pre-doctoral training program in Cellular Approaches to Tissue Engineering and Regeneration (CATER) educates and trains the next generation of scientists in regenerative medicine and tissue engineering. Our multidisciplinary training approach creates researchers that can drive regenerative medicine from the laboratory to the clinic, providing new therapies for human disease and injury.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Institutional National Research Service Award (T32)
Project #
5T32EB001026-10
Application #
8538973
Study Section
Special Emphasis Panel (ZEB1-OSR-C (J1))
Program Officer
Baird, Richard A
Project Start
2003-07-01
Project End
2014-08-31
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
10
Fiscal Year
2013
Total Cost
$274,083
Indirect Cost
$13,191
Name
University of Pittsburgh
Department
Pathology
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
LoPresti, Samuel T; Brown, Bryan N (2018) Effect of Source Animal Age upon Macrophage Response to Extracellular Matrix Biomaterials. J Immunol Regen Med 1:57-66
Russell, Jacquelyn O; Ko, Sungjin; Saggi, Harvinder S et al. (2018) Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration. Am J Pathol 188:1389-1405
Beckwitt, Colin H; Clark, Amanda M; Wheeler, Sarah et al. (2018) Liver 'organ on a chip'. Exp Cell Res 363:15-25
Stahl, Elizabeth C; Haschak, Martin J; Popovic, Branimir et al. (2018) Macrophages in the Aging Liver and Age-Related Liver Disease. Front Immunol 9:2795
Bradshaw, Andrew; Sylakowski, Kyle; Wells, Alan (2018) The Pro-reparative Engine: Stem Cells Aid Healing by Dampening Inflammation. Curr Pathobiol Rep 6:109-115
Ishikawa, Takuro; Hosaka, Yoshinao Z; Beckwitt, Colin et al. (2018) Concomitant attenuation of HMG-CoA reductase expression potentiates the cancer cell growth-inhibitory effect of statins and expands their efficacy in tumor cells with epithelial characteristics. Oncotarget 9:29304-29315
Beckwitt, Colin H; Shiraha, Keisuke; Wells, Alan (2018) Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling. PLoS One 13:e0197422
Brick, Rachel M; Sun, Aaron X; Tuan, Rocky S (2018) Neurotrophically Induced Mesenchymal Progenitor Cells Derived from Induced Pluripotent Stem Cells Enhance Neuritogenesis via Neurotrophin and Cytokine Production. Stem Cells Transl Med 7:45-58
Russell, Jacquelyn O; Monga, Satdarshan P (2018) Wnt/?-Catenin Signaling in Liver Development, Homeostasis, and Pathobiology. Annu Rev Pathol 13:351-378
Missinato, Maria A; Saydmohammed, Manush; Zuppo, Daniel A et al. (2018) Dusp6 attenuates Ras/MAPK signaling to limit zebrafish heart regeneration. Development 145:

Showing the most recent 10 out of 107 publications