This T32 training grant will provide intensive training in Imaging Research with the overall goal of increasing the number of clinician scientists employing imaging in their future research careers. There is an increasingly serious need for such physicians to become the future teachers and mentors in our major clinical specialties. There is a documented shortage of academic radiologists over a number of years now. In particular, Radiology has had a relatively weak history of providing formal training and research opportunities as part of the Clinical Residency Program and yet imaging methodology is now pervading many medical/scientific disciplines. Resident physicians especially in Diagnostic Radiology and Nuclear Medicine Programs will obtain a structured, rigorous research training that they would not normally receive. Didactic coursework will be obtained during the clinical years including identification of training mentors and labs followed by a minimum of 1 to 2 years of formal full time T32 funded research. This will also directly be integrated with existing more advanced training programs including M.S. and Ph.D. degree granting programs in clinical investigation as well as opportunities with basic science and public health programs. At least 25% of all the positions will be open for residents of other departments, explicitly Psychiatry, Neurology, Medicine and Surgery who intend on employing imaging (e.g., Neuro-imaging or interventional imaging) as part of their research careers. By starting early in their careers, we anticipate this may ultimately have a major effect on the career paths these physicians will take. The ultimate outcome will be increased numbers of physicians who will carry out a research career integrated with both basic and applied approaches. The training program will consist of explicit didactic courses prior to the training year, followed by full semester courses during the T32 training years and carefully assigned mentors and laboratories. The faculty is drawn not only from Radiology but from the associated departments and also including Bioengineering and Electrical Engineering. Thus trainees will train not only in Psychiatry, Neurology and Radiology laboratories but in affiliated departments at Johns Hopkins University and Intramural NIH (Baltimore and Bethesda) and potential industrial scientific labs providing a true intra-disciplinary research training experience. Evaluation will include formal progress reports, mock grant preparation and review, as well as publications and required national presentations. The long term goal is to attract resident physicians into a career employing imaging research as a major component of their future academic careers.

National Institute of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Special Emphasis Panel (ZEB1-OSR-C (M1))
Program Officer
Baird, Richard A
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Johns Hopkins University
Schools of Medicine
United States
Zip Code
Plyku, Donika; Mena, Esther; Rowe, Steven P et al. (2018) Combined model-based and patient-specific dosimetry for 18F-DCFPyL, a PSMA-targeted PET agent. Eur J Nucl Med Mol Imaging 45:989-998
Zhong, Bin-Yan; Abiola, Godwin; Weiss, Clifford R (2018) Bariatric Arterial Embolization for Obesity: A Review of Early Clinical Evidence. Cardiovasc Intervent Radiol :
Rubin, Leah H; Sacktor, Ned; Creighton, Jason et al. (2018) Microglial activation is inversely associated with cognition in individuals living with HIV on effective antiretroviral therapy. AIDS 32:1661-1667
Jha, Abhinav K; Mena, Esther; Caffo, Brian et al. (2017) Practical no-gold-standard evaluation framework for quantitative imaging methods: application to lesion segmentation in positron emission tomography. J Med Imaging (Bellingham) 4:011011
Vairavamurthy, Jenanan; Cheskin, Lawrence J; Kraitchman, Dara L et al. (2017) Current and cutting-edge interventions for the treatment of obese patients. Eur J Radiol 93:134-142
Mena, Esther; Taghipour, Mehdi; Sheikhbahaei, Sara et al. (2017) Value of Intratumoral Metabolic Heterogeneity and Quantitative 18F-FDG PET/CT Parameters to Predict Prognosis in Patients With HPV-Positive Primary Oropharyngeal Squamous Cell Carcinoma. Clin Nucl Med 42:e227-e234
Taghipour, Mehdi; Marcus, Charles; Sheikhbahaei, Sara et al. (2017) Clinical Indications and Impact on Management: Fourth and Subsequent Posttherapy Follow-up 18F-FDG PET/CT Scans in Oncology Patients. J Nucl Med 58:737-743
Taghipour, Mehdi; Mena, Esther; Kruse, Matthew J et al. (2017) Post-treatment 18F-FDG-PET/CT versus contrast-enhanced CT in patients with oropharyngeal squamous cell carcinoma: comparative effectiveness study. Nucl Med Commun 38:250-258
Mena, Esther; Sheikhbahaei, Sara; Taghipour, Mehdi et al. (2017) 18F-FDG PET/CT Metabolic Tumor Volume and Intratumoral Heterogeneity in Pancreatic Adenocarcinomas: Impact of Dual-Time Point and Segmentation Methods. Clin Nucl Med 42:e16-e21
Rowe, Steven P; Macura, Katarzyna J; Ciarallo, Anthony et al. (2016) Comparison of Prostate-Specific Membrane Antigen-Based 18F-DCFBC PET/CT to Conventional Imaging Modalities for Detection of Hormone-Naïve and Castration-Resistant Metastatic Prostate Cancer. J Nucl Med 57:46-53

Showing the most recent 10 out of 73 publications