This is the competitive renewal of a T32 training grant that has provided intensive training in Imaging Research with the overall goal of increasing the number of clinician scientists employing imaging in their future research careers. There is an increasingly serious need for such physicians to become the future teachers and mentors in our major clinical specialties. In particular, Radiology has had a relatively weak history of providing formal training and research opportunities as part of the Clinical Residency Program and yet imaging methodology is now pervading many medical/scientific disciplines. Given the interdisciplinary nature of imaging, we have been fortunate to be able to include in addition to Radiology, T32 proposed departments/programs such as General Internal Medicine, Neurology, Neuropathology, Psychiatry, Surgery, and in this renewal, Oncology and Pediatric trainees. During the last 4 years and expected year 5, we have successfully filled the majority of our slots uniquely co-funded by several NIH institutes. Non-faculty residents and fellowship physicians, especially in Radiology and the T32 proposed departments/programs, will obtain a structured, rigorous research training that they would not normally receive. Didactic coursework will be obtained during the clinical years including identification of training mentors and labs followed b a minimum of 1 to 2 years of formal full- time T32 funded research. This also will directly be integrated with existing more advanced training programs, including M.S and Ph.D. degree granting programs and clinical investigation, as well as opportunities and basic science and public health programs. By starting early in their careers, we anticipate this may ultimately have a major effect on the career paths these trainee physicians will take. The ultimate outcome will be increased numbers of physicians who will carry out a research career integrated with both basic and applied approaches. The training program will consist of explicit didactic courses prior to the training year, followed by a full semester of courses during the T32 training years and carefully assigned mentors and laboratories. The faculty is drawn not only from Radiology but from the associated basic departments including Bioengineering, Electrical Engineering, Psychology, and Public Health. Thus, trainees will train not only in Radiology and the other T32 proposed department/program laboratories, but in affiliated departments at Johns Hopkins University and Intramural NIH (Baltimore and Bethesda), as well as potential industrial scientific labs, providing a true intra-disciplinary research training experience. Evaluation will include formal progress reports, mock grant preparation and review, as well as publications and required national presentations. The long-term goal is to attract resident physicians into a career employing imaging research as a major component of their future academic careers.

Public Health Relevance

This application is a competitive renewal of an existing 5 year T32 training grant. The mission of this grant has been to address the growing problem of recruitment and retention of physicians in academia by providing a 1 to 2 year rigorous program in imaging research. We have successfully trained a large number of not only radiologists and nuclear medicine physicians, but a number of physicians at the residency and fellowship level (prior to faculty level) from a number of disciplines who will utilize their experience in imaging research towards their future research careers.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Institutional National Research Service Award (T32)
Project #
5T32EB006351-08
Application #
8677596
Study Section
Special Emphasis Panel (ZEB1)
Program Officer
Baird, Richard A
Project Start
2006-09-30
Project End
2017-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
8
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Plyku, Donika; Mena, Esther; Rowe, Steven P et al. (2018) Combined model-based and patient-specific dosimetry for 18F-DCFPyL, a PSMA-targeted PET agent. Eur J Nucl Med Mol Imaging 45:989-998
Zhong, Bin-Yan; Abiola, Godwin; Weiss, Clifford R (2018) Bariatric Arterial Embolization for Obesity: A Review of Early Clinical Evidence. Cardiovasc Intervent Radiol :
Rubin, Leah H; Sacktor, Ned; Creighton, Jason et al. (2018) Microglial activation is inversely associated with cognition in individuals living with HIV on effective antiretroviral therapy. AIDS 32:1661-1667
Jha, Abhinav K; Mena, Esther; Caffo, Brian et al. (2017) Practical no-gold-standard evaluation framework for quantitative imaging methods: application to lesion segmentation in positron emission tomography. J Med Imaging (Bellingham) 4:011011
Vairavamurthy, Jenanan; Cheskin, Lawrence J; Kraitchman, Dara L et al. (2017) Current and cutting-edge interventions for the treatment of obese patients. Eur J Radiol 93:134-142
Mena, Esther; Taghipour, Mehdi; Sheikhbahaei, Sara et al. (2017) Value of Intratumoral Metabolic Heterogeneity and Quantitative 18F-FDG PET/CT Parameters to Predict Prognosis in Patients With HPV-Positive Primary Oropharyngeal Squamous Cell Carcinoma. Clin Nucl Med 42:e227-e234
Taghipour, Mehdi; Marcus, Charles; Sheikhbahaei, Sara et al. (2017) Clinical Indications and Impact on Management: Fourth and Subsequent Posttherapy Follow-up 18F-FDG PET/CT Scans in Oncology Patients. J Nucl Med 58:737-743
Taghipour, Mehdi; Mena, Esther; Kruse, Matthew J et al. (2017) Post-treatment 18F-FDG-PET/CT versus contrast-enhanced CT in patients with oropharyngeal squamous cell carcinoma: comparative effectiveness study. Nucl Med Commun 38:250-258
Mena, Esther; Sheikhbahaei, Sara; Taghipour, Mehdi et al. (2017) 18F-FDG PET/CT Metabolic Tumor Volume and Intratumoral Heterogeneity in Pancreatic Adenocarcinomas: Impact of Dual-Time Point and Segmentation Methods. Clin Nucl Med 42:e16-e21
Rowe, Steven P; Macura, Katarzyna J; Ciarallo, Anthony et al. (2016) Comparison of Prostate-Specific Membrane Antigen-Based 18F-DCFBC PET/CT to Conventional Imaging Modalities for Detection of Hormone-Naïve and Castration-Resistant Metastatic Prostate Cancer. J Nucl Med 57:46-53

Showing the most recent 10 out of 73 publications