This training grant was initiated in 1967 and has trained or is training 57 predoctoral students and postdoctoral trainees. The purpose of the program is to provide scientific training to pre- and postdoctoral trainees in biochemical, molecular, and environmental toxicology. Students in the program may enter one of three Ph.D. tracks, general toxicology, molecular toxicology, or environmental toxicology. Students must also have a minor in another field such as pharmacology, biochemistry, cell biology, statistics, microbiology or biotechnology. This training program has 12 preceptors whose research areas include molecular biology, xenobiotic metabolism, dermatoxicology, chemical carcinogenesis, oxyradicals, analytical toxicology, reproductive toxicology and pesticide toxicology.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Institutional National Research Service Award (T32)
Project #
5T32ES007046-23
Application #
2872280
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
1977-07-01
Project End
2002-06-30
Budget Start
1999-07-01
Budget End
2000-06-30
Support Year
23
Fiscal Year
1999
Total Cost
Indirect Cost
Name
North Carolina State University Raleigh
Department
Pharmacology
Type
Schools of Earth Sciences/Natur
DUNS #
City
Raleigh
State
NC
Country
United States
Zip Code
27695
Duke, Katherine S; Thompson, Elizabeth A; Ihrie, Mark D et al. (2018) Role of p53 in the chronic pulmonary immune response to tangled or rod-like multi-walled carbon nanotubes. Nanotoxicology :1-17
Green, Adrian J; Hoyo, Cathrine; Mattingly, Carolyn J et al. (2018) Cadmium exposure increases the risk of juvenile obesity: a human and zebrafish comparative study. Int J Obes (Lond) 42:1285-1295
Messenger, Zachary J; Hall, Jonathan R; Jima, Dereje D et al. (2018) C/EBP? deletion in oncogenic Ras skin tumors is a synthetic lethal event. Cell Death Dis 9:1054
Green, Adrian J; Planchart, Antonio (2018) The neurological toxicity of heavy metals: A fish perspective. Comp Biochem Physiol C Toxicol Pharmacol 208:12-19
Duke, Katherine S; Bonner, James C (2018) Mechanisms of carbon nanotube-induced pulmonary fibrosis: a physicochemical characteristic perspective. Wiley Interdiscip Rev Nanomed Nanobiotechnol 10:e1498
Duke, Katherine S; Taylor, Alexia J; Ihrie, Mark D et al. (2018) Signal Transducer and Activator of Transcription 1 Regulates Multiwalled Carbon Nanotube-induced Pulmonary Fibrosis in Mice via Suppression of Transforming Growth Factor-?1 Production and Signaling. Ann Am Thorac Soc 15:S129-S130
Planchart, Antonio; Green, Adrian; Hoyo, Cathrine et al. (2018) Heavy Metal Exposure and Metabolic Syndrome: Evidence from Human and Model System Studies. Curr Environ Health Rep 5:110-124
Miyazawa, Masaki; Bogdan, Alexander R; Tsuji, Yoshiaki (2018) Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2. Cell Chem Biol :
Ihrie, Mark D; Bonner, James C (2018) The Toxicology of Engineered Nanomaterials in Asthma. Curr Environ Health Rep 5:100-109
Miyazawa, Masaki; Bogdan, Alexander R; Hashimoto, Kazunori et al. (2018) Regulation of transferrin receptor-1 mRNA by the interplay between IRE-binding proteins and miR-7/miR-141 in the 3'-IRE stem-loops. RNA 24:468-479

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