The purpose of this program is to provide comprehensive training in environmental toxicology coupling strong discipline foundations to applications in the broad field of toxicology. Thirteen core faculty in the graduate program will serve as mentors/thesis directors for trainees. Cellular/molecular toxicology and medicine, immunotoxicology, neuropharmacology and neurobehavioral toxicology, and environmental/aquatic toxicology are emphasis areas in which trainees perform research. The major intent of the program is to provide students and postdoctorals intensive academic and research training in the sub-disciplines of toxicology, but also preparation via courses, seminars, and peer interactions for addressing complex issues.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Institutional National Research Service Award (T32)
Project #
5T32ES007052-23
Application #
2872282
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
1978-01-01
Project End
2002-06-30
Budget Start
1999-07-01
Budget End
2000-06-30
Support Year
23
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Cornell University
Department
Microbiology/Immun/Virology
Type
Schools of Veterinary Medicine
DUNS #
City
Ithaca
State
NY
Country
United States
Zip Code
14850
von Stein, Richard T; Silver, Kristopher S; Soderlund, David M (2013) Indoxacarb, Metaflumizone, and Other Sodium Channel Inhibitor Insecticides: Mechanism and Site of Action on Mammalian Voltage-Gated Sodium Channels. Pestic Biochem Physiol 106:101-112
Murdoch, Robert W; Hay, Anthony G (2013) Genetic and chemical characterization of ibuprofen degradation by Sphingomonas Ibu-2. Microbiology 159:621-32
Vayndorf, Elena M; Lee, Siu Sylvia; Liu, Rui Hai (2013) Whole apple extracts increase lifespan, healthspan and resistance to stress in Caenorhabditis elegans. J Funct Foods 5:1236-1243
Braun, A A; Herring, N R; Schaefer, T L et al. (2011) Neurotoxic (+)-methamphetamine treatment in rats increases brain-derived neurotrophic factor and tropomyosin receptor kinase B expression in multiple brain regions. Neuroscience 184:164-71
Silver, Kristopher S; Soderlund, David M (2007) Point mutations at the local anesthetic receptor site modulate the state-dependent block of rat Na v1.4 sodium channels by pyrazoline-type insecticides. Neurotoxicology 28:655-63
Lamkin, Thomas J; Chin, Vivian; Varvayanis, Susi et al. (2006) Retinoic acid-induced CD38 expression in HL-60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels. J Cell Biochem 97:1328-38
Lamkin, Thomas J; Chin, Vivian; Yen, Andrew (2006) All-trans retinoic acid induces p62DOK1 and p56DOK2 expression which enhances induced differentiation and G0 arrest of HL-60 leukemia cells. Am J Hematol 81:603-15
Silver, Kristopher S; Soderlund, David M (2006) Differential sensitivity of rat voltage-sensitive sodium channel isoforms to pyrazoline-type insecticides. Toxicol Appl Pharmacol 214:209-17
Greenblatt, Rebecca J; Work, Thierry M; Dutton, Peter et al. (2005) Geographic variation in marine turtle fibropapillomatosis. J Zoo Wildl Med 36:527-30
Greenblatt, Rebecca J; Quackenbush, Sandra L; Casey, Rufina N et al. (2005) Genomic variation of the fibropapilloma-associated marine turtle herpesvirus across seven geographic areas and three host species. J Virol 79:1125-32

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