Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Institutional National Research Service Award (T32)
Project #
5T32ES007263-08
Application #
2331555
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
1990-07-01
Project End
2000-06-30
Budget Start
1997-07-01
Budget End
1998-06-30
Support Year
8
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Pharmacology
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Kwegyir-Afful, Andrew K; Bruno, Robert D; Purushottamachar, Puranik et al. (2016) Galeterone and VNPT55 disrupt Mnk-eIF4E to inhibit prostate cancer cell migration and invasion. FEBS J 283:3898-3918
Aurelian, Laure; Bollino, Dominique; Colunga, Aric (2016) The oncolytic virus ?PK has multimodal anti-tumor activity. Pathog Dis 74:
Mullins, Roger J; Xu, Su; Pereira, Edna F R et al. (2015) Prenatal exposure of guinea pigs to the organophosphorus pesticide chlorpyrifos disrupts the structural and functional integrity of the brain. Neurotoxicology 48:9-20
Mistry, Pragnesh; Laird, Michelle H W; Schwarz, Ryan S et al. (2015) Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain. Proc Natl Acad Sci U S A 112:5455-60
Colunga, A; Bollino, D; Schech, A et al. (2014) Calpain-dependent clearance of the autophagy protein p62/SQSTM1 is a contributor to ?PK oncolytic activity in melanoma. Gene Ther 21:371-8
Mullins, Roger J; Xu, Su; Pereira, Edna F R et al. (2013) Delayed hippocampal effects from a single exposure of prepubertal guinea pigs to sub-lethal dose of chlorpyrifos: a magnetic resonance imaging and spectroscopy study. Neurotoxicology 36:42-8
Patrick, B A; Jaiswal, A K (2012) Stress-induced NQO1 controls stability of C/EBP* against 20S proteasomal degradation to regulate p63 expression with implications in protection against chemical-induced skin cancer. Oncogene 31:4362-71
Patrick, Brad A; Das, Amitava; Jaiswal, Anil K (2012) NAD(P)H:quinone oxidoreductase 1 protects bladder epithelium against painful bladder syndrome in mice. Free Radic Biol Med 53:1886-93
Bruno, Robert D; Vasaitis, Tadas S; Gediya, Lalji K et al. (2011) Synthesis and biological evaluations of putative metabolically stable analogs of VN/124-1 (TOK-001): head to head anti-tumor efficacy evaluation of VN/124-1 (TOK-001) and abiraterone in LAPC-4 human prostate cancer xenograft model. Steroids 76:1268-79
Patrick, B A; Gong, X; Jaiswal, A K (2011) Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancer. Oncogene 30:1098-107

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