Abstract

This is an application for continuation of an interdisciplinary training program in which three academic programs participate. The program includes provision for a two year research fellowship emphasizing environmental lung disease with patient-oriented research of asthma, fibrosis, lung cancer, and the pulmonary response to environmental toxicants. Studies are basic science oriented with emphasis on cytokine and growth factor gene regulation, receptor expression and signal transduction, oncogenes, and tumor suppressor genes. Twenty-two preceptors with expertise in research fellowship training in mechanisms of disease pertinent to the goals in the environmental health sciences are participants. Research fellows develop their own projects and seven have presented their research at national meetings.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Institutional National Research Service Award (T32)
Project #
5T32ES007267-09
Application #
6150701
Study Section
Environmental Health Sciences Review Committee (EHS)
Program Officer
Shreffler, Carol K
Project Start
1992-07-01
Project End
2002-06-30
Budget Start
2000-07-01
Budget End
2001-06-30
Support Year
9
Fiscal Year
2000
Total Cost
$205,557
Indirect Cost

  Institution

Name
New York University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016

  Publications

Varga, Andrew W; Ducca, Emma L; Kishi, Akifumi et al. (2016) Effects of aging on slow-wave sleep dynamics and human spatial navigational memory consolidation. Neurobiol Aging 42:142-149
Berger, Kenneth I; Turetz, Meredith; Liu, Mengling et al. (2015) Oscillometry complements spirometry in evaluation of subjects following toxic inhalation. ERJ Open Res 1:
Kugler, Matthias C; Joyner, Alexandra L; Loomis, Cynthia A et al. (2015) Sonic hedgehog signaling in the lung. From development to disease. Am J Respir Cell Mol Biol 52:1-13
Wu, Feng; Rom, William N; Koshiji, Minori et al. (2015) Role of GLI1 and NDRG1 in Increased Resistance to Apoptosis Induction. J Environ Pathol Toxicol Oncol 34:213-25
Tsay, Jun-Chieh J; Li, Zhiguo; Yie, Ting-An et al. (2015) Molecular characterization of the peripheral airway field of cancerization in lung adenocarcinoma. PLoS One 10:e0118132
Tsukiji, Jun; Cho, Soo Jung; Echevarria, Ghislaine C et al. (2014) Lysophosphatidic acid and apolipoprotein A1 predict increased risk of developing World Trade Center-lung injury: a nested case-control study. Biomarkers 19:159-65
Varga, Andrew W; Kang, Mihwa; Ramesh, Priyanka V et al. (2014) Effects of acute sleep deprivation on motor and reversal learning in mice. Neurobiol Learn Mem 114:217-22
Nolan, Anna; Kwon, Sophia; Cho, Soo Jung et al. (2014) MMP-2 and TIMP-1 predict healing of WTC-lung injury in New York City firefighters. Respir Res 15:5
Varga, Andrew W; Kishi, Akifumi; Mantua, Janna et al. (2014) Apnea-induced rapid eye movement sleep disruption impairs human spatial navigational memory. J Neurosci 34:14571-7
Bleck, Bertram; Grunig, Gabriele; Chiu, Amanda et al. (2013) MicroRNA-375 regulation of thymic stromal lymphopoietin by diesel exhaust particles and ambient particulate matter in human bronchial epithelial cells. J Immunol 190:3757-63

Showing the most recent 10 out of 39 publications