This training application is an interdepartmental and interdisciplinary program in Molecular Epidemiology in Children's Environmental Health (MECEH). Participating training faculty are from three interactive departments and include the Departments of Environmental Health, Pediatrics, and Molecular Genetics. The program focus is to identify outstanding pre-doctoral, and postdoctoral M.D.s and Ph.D.s and equip each with the knowledge base to undertake epidemiological and clinical studies using molecular markers of exposure, effect and susceptibility. These studies will examine the impact of environmental exposures on complex diseases in children's health. The program will provide training at three levels: the pre-doctoral student achieving a Ph.D. degree, the postdoctoral trainee with a Ph.D., and the M.D. postdoctoral pediatric resident seeking a M.S. degree in epidemiology. Entering pre- doctoral trainees will have the equivalent of an undergraduate degree majoring in biology, molecular biology, molecular genetics, mathematics or a related field having obtained superior academic achievements and a GRE of 1800 or better. Postdoctoral candidates must have proven academic accomplishments and hold the degrees of Ph.D. or M.D. The physicians should have completed three years their pediatric residency and have demonstrated scholarship. All trainees will have a specific interest in the use of cutting-edge molecular methods to understand the impact of environmental exposures on children's health. Requested for the first year are 2 pre-doctoral, 1 postdoctoral Ph.D. and 2 postdoctoral M.D. trainees. The physical facilities all contain modern well-equipped laboratories and computer facilities. Being one of 21 NIEHS Centers and the first Center for Environmental Genetics, the trainees are provided with optimum laboratory resources in a highly collaborative environment. Nationally, the MECEH program fulfills a critical need to train researchers at the pre-doctoral and postdoctoral levels with combined understanding and research skills in pediatric epidemiology, biostatistics, molecular biology and toxicology, and genetics. Institutionally, this program will further collaborations and empower trainees to utilize the best scientific approaches that these disciplines offer.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Institutional National Research Service Award (T32)
Project #
5T32ES010957-05
Application #
6917302
Study Section
Environmental Health Sciences Review Committee (EHS)
Program Officer
Shreffler, Carol K
Project Start
2001-08-15
Project End
2006-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
5
Fiscal Year
2005
Total Cost
$505,781
Indirect Cost
Name
University of Cincinnati
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
041064767
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Vuong, Ann M; Yolton, Kimberly; Poston, Kendra L et al. (2018) Childhood polybrominated diphenyl ether (PBDE) exposure and executive function in children in the HOME Study. Int J Hyg Environ Health 221:87-94
Biagini Myers, Jocelyn M; Schauberger, Eric; He, Hua et al. (2018) A Pediatric Asthma Risk Score to better predict asthma development in young children. J Allergy Clin Immunol :
McWhorter, Ketrell L; Bowers, Katherine; Dolan, Lawrence M et al. (2018) Impact of gestational weight gain and prepregnancy body mass index on the prevalence of large-for-gestational age infants in two cohorts of women with type 1 insulin-dependent diabetes: a cross-sectional population study. BMJ Open 8:e019617
Kim, Stephani; Xu, Xijin; Zhang, Yuling et al. (2018) Metal concentrations in pregnant women and neonates from informal electronic waste recycling. J Expo Sci Environ Epidemiol :
Jose, S; Abhyankar, M M; Mukherjee, A et al. (2018) Leptin receptor q223r polymorphism influences neutrophil mobilization after Clostridium difficile infection. Mucosal Immunol 11:947-957
Giannini, Courtney M; Herrick, Robert L; Buckholz, Jeanette M et al. (2018) Comprehension and perceptions of study participants upon receiving perfluoroalkyl substance exposure biomarker results. Int J Hyg Environ Health 221:1040-1046
Vuong, Ann M; Braun, Joseph M; Webster, Glenys M et al. (2018) Polybrominated diphenyl ether (PBDE) exposures and thyroid hormones in children at age 3?years. Environ Int 117:339-347
McWhorter, Ketrell L; Bowers, Katherine; Dolan, Lawrence et al. (2018) Assessing the Impact of Excessive Gestational Weight Gain Among Women With Type 1 Diabetes on Overweight/Obesity in Their Adolescent and Young Adult Offspring: A Pilot Study. Front Endocrinol (Lausanne) 9:713
Vuong, Ann M; Yolton, Kimberly; Poston, Kendra L et al. (2017) Prenatal and postnatal polybrominated diphenyl ether (PBDE) exposure and measures of inattention and impulsivity in children. Neurotoxicol Teratol 64:20-28
Collins, M H; Martin, L J; Alexander, E S et al. (2017) Newly developed and validated eosinophilic esophagitis histology scoring system and evidence that it outperforms peak eosinophil count for disease diagnosis and monitoring. Dis Esophagus 30:1-8

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