The University of Washington Department of Biostatistics, with the collaboration of faculty from the Departments of Computer Sciences, Epidemiology, Genome Sciences, Medicine, Pathology, Environmental and Occupational Health Sciences, and Statistics proposes to train biostatisticians and life scientists to develop and apply quantitative methods to the environmental health sciences in a new program """"""""Biostatistics, Epidemiologic and Bioinfomatic Training in the Environmental Health Sciences."""""""" The proposed Training Program has two pathways: one population-based and one laboratory-based. The population-based pathway will emphasize statistical methods in environmental epidemiology to elucidate the etiologies of environmentally-related diseases. The laboratory-based pathway will focus on the interpretation of modern genomic data and how they may be exploited to unravel the biological bases of these diseases. Both pathways will foster a multidisciplinary, collaborative and interdisciplinary training environment that 1) includes quantitative and applied training objectives, 2) assigns a quantitative and a scientific mentor to each trainee, 3) involves each trainee in a project that leads to expertise in multiple disciplines necessary to advance environmental health science research, 4) recruits trainees with differing backgrounds to enhance cross-training, and 5) targets training activities to enhance training goals. The investigators propose a trainee recruitment strategy that will start with four pre-doctoral and two postdoctoral trainees and build to eight pre-doctoral and four post-doctoral trainees in year five. Trainees will be recruited from multiple disciplines and each will have an individualized Training Program unified under the common theme of developing quantitative skills for application to the environmental health sciences. The pre-doctoral trainees will pursue Ph.D. degrees in biostatistics, environmental health, epidemiology, or genome sciences, whereas the postdoctoral trainees will be eligible to seek MPH or MS degrees in an appropriate discipline. These trainees will be mentored by an outstanding group of 23 faculty drawn from the collaborating departments, all of whom have substantial training and research records. The preceptors will direct the trainee's research as well as contribute to teaching their courses and providing training in the ethical conduct of research and the management of laboratory and population studies. BACKGROUND There have been substantive changes to the application since the initial submission. The description of the pre-doctoral program has been expanded to provide specific detail on the curriculum. Examples have been provided of the dual mentoring program and how it leads to program integration. The dual mentorship arrangement has been modified so that at least one of the mentors has current NIEHS funding. The requirement that trainees sign a statement of intent to pursue environmental health science training has been deleted. Details have been provided on how the trainees will be assigned to mentors. The time that trainees will spend in research in their initial years has been clarified and justified. There has been clarification given about how mentors can been changed as a trainee's research topic is chosen. An evaluation form has been provided for assessing a trainee's presentation skills. Dr. Weir's role as Associate Director has been re-structured. The tracking system of alumni of the program has been modified to capture environmental health science activities. Explanation has been provided about the use of T32 support for the first 3 years of training. The role of the dual mentors on the same research project has been clarified. The proposed number of trainees to be supported has been reduced to 4 pre-doctoral and 2 postdoctoral in the initial year, ramping up to 8 pre-doctoral and 4 postdoctoral by year 5.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Institutional National Research Service Award (T32)
Project #
1T32ES015459-01A2
Application #
7629890
Study Section
Environmental Health Sciences Review Committee (EHS)
Program Officer
Shreffler, Carol K
Project Start
2009-07-01
Project End
2014-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
1
Fiscal Year
2009
Total Cost
$265,656
Indirect Cost
Name
University of Washington
Department
Biostatistics & Other Math Sci
Type
Schools of Public Health
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Tarr, Gillian A M; Oltean, Hanna N; Phipps, Amanda I et al. (2018) Strength of the association between antibiotic use and hemolytic uremic syndrome following Escherichia coli O157:H7 infection varies with case definition. Int J Med Microbiol 308:921-926
Riley, Erin A; Carpenter, Emily E; Ramsay, Joemy et al. (2018) Evaluation of 1-Nitropyrene as a Surrogate Measure for Diesel Exhaust. Ann Work Expo Health 62:339-350
Keller, Joshua P; Rice, Kenneth M (2018) Selecting Shrinkage Parameters for Effect Estimation: The Multi-Ethnic Study of Atherosclerosis. Am J Epidemiol 187:358-365
Tessum, Mei W; Larson, Timothy; Gould, Timothy R et al. (2018) Mobile and Fixed-Site Measurements To Identify Spatial Distributions of Traffic-Related Pollution Sources in Los Angeles. Environ Sci Technol 52:2844-2853
Zhou, Nicolette Angela; Fagnant-Sperati, Christine Susan; Shirai, Jeffry Hiroshi et al. (2018) Evaluation of the bag-mediated filtration system as a novel tool for poliovirus environmental surveillance: Results from a comparative field study in Pakistan. PLoS One 13:e0200551
Tarr, Gillian A M; Shringi, Smriti; Phipps, Amanda I et al. (2018) Geogenomic Segregation and Temporal Trends of Human Pathogenic Escherichia coli O157:H7, Washington, USA, 2005-20141. Emerg Infect Dis 24:32-39
Shaffer, Rachel M; Gilbert, Steven G (2018) Reducing occupational lead exposures: Strengthened standards for a healthy workforce. Neurotoxicology 69:181-186
Engen, Rachel M; Park, Giulia E; Schumacher, Cooper S et al. (2018) Donor-specific Antibody Surveillance and Graft Outcomes in Pediatric Kidney Transplant Recipients. Transplantation 102:2072-2079
Trasande, Leonardo; Shaffer, Rachel M; Sathyanarayana, Sheela et al. (2018) Food Additives and Child Health. Pediatrics 142:
Hooper, Laura G; Young, Michael T; Keller, Joshua P et al. (2018) Ambient Air Pollution and Chronic Bronchitis in a Cohort of U.S. Women. Environ Health Perspect 126:027005

Showing the most recent 10 out of 110 publications