The proposed Research Training Program will train predoctoral students broadly in the discipline of genetics at the University of Wisconsin - Madison. Students admitted to the Genetics graduate program at Wisconsin will be supported for two years of graduate studies: the first year and a subsequent year after completing all required coursework and qualifying examinations. The Genetics graduate program presently consists of 79 faculty representing 20 different departments in the biological sciences and 53 students studying with 28 different faculty trainers. The collective research interests of program faculty and students encompass virtually the entire breadth and depth of contemporary genetics. Trainees are selected based on prior academic achievements, research experience, and personal interviews conducted before acceptance into the program. Accepted students identify Genetics as their primary academic pursuit and choose thesis advisors based on their individual research interests The Genetics doctoral program is a campus-wide training program administered by the Laboratory of Genetics, which is housed in a modern state-of-the-art research facility. Supported students complete a rigorous academic program consisting of both formal coursework and individualized mentoring in genetics. Formal coursework includes a core curriculum of required genetics courses, specialized electives identified by students together with their Thesis Advisory Committee, a course in the responsible conduct of research (RCR), and continuing exposure to RCR-related issues throughout the graduate career. Students gain teaching and communication experience by serving for one semester as a Teaching Assistant for an undergraduate Genetics course and by presenting their research in formal settings before faculty and students of the program. Student performance is evaluated by a two-part qualifying examination that tests understanding of broad genetic principles and an ability to propose, execute, and defend a thesis research project. Each student's progress is monitored annually by a Thesis Advisory Committee. The Genetics Training Grant develops young investigators as independent scientists by providing a rigorous and broad education in the science of genetics. Our graduates bring the methods and logic of genetic analysis to bear on contemporary research problems. Our long range goal is to educate new generations of professional geneticists who will advance the biological research sciences using genetic approaches and methodologies.

Public Health Relevance

Genetics is a fundamental discipline of contemporary biomedical research. It is both a tool for discovery and an consistent logic for in-depth understanding of biological mechanisms, especially those that relate to inherited human disease. The University of Wisconsin graduate program in Genetics trains young investigators broadly in the science of genetics and, by doing so, develops future generations of professional biomedical researchers.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
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Training and Workforce Development Subcommittee - D (TWD)
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Haynes, Susan R
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University of Wisconsin Madison
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United States
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Krause, David J; Kominek, Jacek; Opulente, Dana A et al. (2018) Functional and evolutionary characterization of a secondary metabolite gene cluster in budding yeasts. Proc Natl Acad Sci U S A 115:11030-11035
Rytz, Thérèse C; Miller, Marcus J; McLoughlin, Fionn et al. (2018) SUMOylome Profiling Reveals a Diverse Array of Nuclear Targets Modified by the SUMO Ligase SIZ1 during Heat Stress. Plant Cell 30:1077-1099
Muir, Virginia S; Gasch, Audrey P; Anderson, Philip (2018) The Substrates of Nonsense-Mediated mRNA Decay in Caenorhabditis elegans. G3 (Bethesda) 8:195-205
Schwahn, Denise J; Wang, Richard J; White, Michael A et al. (2018) Genetic Dissection of Hybrid Male Sterility Across Stages of Spermatogenesis. Genetics 210:1453-1465
Hvala, John A; Frayer, Megan E; Payseur, Bret A (2018) Signatures of hybridization and speciation in genomic patterns of ancestry. Evolution :
Nantie, Leah B; Young, Randee E; Paltzer, Wyatt G et al. (2018) Lats1/2 inactivation reveals Hippo function in alveolar type I cell differentiation during lung transition to air breathing. Development 145:
Pfannenstiel, Brandon T; Greco, Claudio; Sukowaty, Andrew T et al. (2018) The epigenetic reader SntB regulates secondary metabolism, development and global histone modifications in Aspergillus flavus. Fungal Genet Biol 120:9-18
Pleiman, Jennifer K; Irving, Amy A; Wang, Zhishi et al. (2018) The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer. PLoS Genet 14:e1007611
Lind, Abigail L; Lim, Fang Yun; Soukup, Alexandra A et al. (2018) An LaeA- and BrlA-Dependent Cellular Network Governs Tissue-Specific Secondary Metabolism in the Human Pathogen Aspergillus fumigatus. mSphere 3:
Parmenter, Michelle D; Nelson, Jacob P; Weigel, Sara E et al. (2018) Masticatory Apparatus Performance and Functional Morphology in the Extremely Large Mice from Gough Island. Anat Rec (Hoboken) :

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