Case Western Reserve University School of Medicine (CWRU SOM) has provided integrated MD-PhD training since 1956 with many distinguished alumni, including two Nobel laureates. The NIH-funded CWRU Medical Scientist Training Program (MSTP) was started in 1975 (T32 GM07250) and has 107 current students. Research and clinical training occurs at CWRU and affiliated institutions (University Hospitals Cleveland Medical Center, Cleveland Clinic, MetroHealth Medical Center and the Louis Stokes Veteran?s Administration Medical Center). These sites are well equipped for cutting edge research and state of the art clinical training. The CWRU MSTP curriculum integrates scientific and clinical instruction in all three phases: both PhD and MD course work during the first two years, substantial personalized clinical instruction as well as research during the PhD years, and clinical clerkships, clinical electives and research electives in the final phase. PhD mentors provide individualized research training. Active mentors are well supported by NIH research grants or other funding sources; they also have established research training track records or, in the case of Initial Mentors, will be paired with a Senior Mentor to insure effective mentoring of trainees and to develop the mentoring skills of new trainers. Criteria for acceptance of MSTP students include superior academic performance and evidence of strong commitment and skills for research. Acceptance by the MSTP automatically admits a student to the SOM and any of the 14 MSTP-affiliated PhD programs. All CWRU MSTP students receive full financial support for stipend, tuition and health fees for all phases of the program (8.3 years mean duration), and the program provides laptop computers and travel awards for students to attend national research meetings. Numerous MSTP-specific program activities supplement the PhD and MD curricula. The program emphasizes development of leadership skills through student governance, faculty mentoring, and student-led program activities.

Public Health Relevance

The CWRU Medical Scientist Training Program integrates research and clinical training of physician scientists in basic and translational biomedical sciences. Training in these areas can then be applied to a wide range of basic, translational and clinical research. Our mission is to train MD-PhD students for productive careers in biomedical research to fill the national need for future physician-scientists.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
3T32GM007250-45S1
Application #
10183382
Study Section
NIGMS Initial Review Group (TWD)
Program Officer
Maas, Stefan
Project Start
1975-07-01
Project End
2021-06-30
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
45
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Pathology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Gunalan, Kabilar; Howell, Bryan; McIntyre, Cameron C (2018) Quantifying axonal responses in patient-specific models of subthalamic deep brain stimulation. Neuroimage 172:263-277
Hanson, Gavin; Alhusaini, Najwa; Morris, Nathan et al. (2018) Translation elongation and mRNA stability are coupled through the ribosomal A-site. RNA 24:1377-1389
Anderson, Christian E; Wang, Charlie Y; Gu, Yuning et al. (2018) Regularly incremented phase encoding - MR fingerprinting (RIPE-MRF) for enhanced motion artifact suppression in preclinical cartesian MR fingerprinting. Magn Reson Med 79:2176-2182
Gu, Yuning; Wang, Charlie Y; Anderson, Christian E et al. (2018) Fast magnetic resonance fingerprinting for dynamic contrast-enhanced studies in mice. Magn Reson Med 80:2681-2690
Babinchak, W Michael; Li, Zhenlu; Buck, Matthias (2018) Keys to Amyloid City: Computation and NMR Reveal Potential TDP-43 ALS Intermediates. Biophys J 115:1625-1627
Marcott, Pamela F; Gong, Sheng; Donthamsetti, Prashant et al. (2018) Regional Heterogeneity of D2-Receptor Signaling in the Dorsal Striatum and Nucleus Accumbens. Neuron 98:575-587.e4
Otegbeye, Folashade; Ojo, Evelyn; Moreton, Stephen et al. (2018) Correction: Inhibiting TGF-beta signaling preserves the function of highly activated, in vitro expanded natural killer cells in AML and colon cancer models. PLoS One 13:e0197008
Vernekar, Amit A; Berger, Gilles; Czapar, Anna E et al. (2018) Speciation of Phenanthriplatin and Its Analogs in the Core of Tobacco Mosaic Virus. J Am Chem Soc 140:4279-4287
Lempka, Scott F; Howell, Bryan; Gunalan, Kabilar et al. (2018) Characterization of the stimulus waveforms generated by implantable pulse generators for deep brain stimulation. Clin Neurophysiol 129:731-742
Wang, Xiuxing; Prager, Briana C; Wu, Qiulian et al. (2018) Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression. Cell Stem Cell 22:514-528.e5

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