Case Western Reserve University School of Medicine (CWRU SOM) has provided integrated MD-PhD training since 1956 with many distinguished alumni, including two Nobel laureates. The NIH-funded CWRU Medical Scientist Training Program (MSTP) was started in 1975 (T32 GM07250) and has 107 current students. Research and clinical training occurs at CWRU and affiliated institutions (University Hospitals Cleveland Medical Center, Cleveland Clinic, MetroHealth Medical Center and the Louis Stokes Veteran?s Administration Medical Center). These sites are well equipped for cutting edge research and state of the art clinical training. The CWRU MSTP curriculum integrates scientific and clinical instruction in all three phases: both PhD and MD course work during the first two years, substantial personalized clinical instruction as well as research during the PhD years, and clinical clerkships, clinical electives and research electives in the final phase. PhD mentors provide individualized research training. Active mentors are well supported by NIH research grants or other funding sources; they also have established research training track records or, in the case of Initial Mentors, will be paired with a Senior Mentor to insure effective mentoring of trainees and to develop the mentoring skills of new trainers. Criteria for acceptance of MSTP students include superior academic performance and evidence of strong commitment and skills for research. Acceptance by the MSTP automatically admits a student to the SOM and any of the 14 MSTP-affiliated PhD programs. All CWRU MSTP students receive full financial support for stipend, tuition and health fees for all phases of the program (8.3 years mean duration), and the program provides laptop computers and travel awards for students to attend national research meetings. Numerous MSTP-specific program activities supplement the PhD and MD curricula. The program emphasizes development of leadership skills through student governance, faculty mentoring, and student-led program activities.

Public Health Relevance

The CWRU Medical Scientist Training Program integrates research and clinical training of physician scientists in basic and translational biomedical sciences. Training in these areas can then be applied to a wide range of basic, translational and clinical research. Our mission is to train MD-PhD students for productive careers in biomedical research to fill the national need for future physician-scientists.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
3T32GM007250-45S1
Application #
10183382
Study Section
NIGMS Initial Review Group (TWD)
Program Officer
Maas, Stefan
Project Start
1975-07-01
Project End
2021-06-30
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
45
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Pathology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Gulati, N M; Pitek, A S; Czapar, A E et al. (2018) The in vivo fates of plant viral nanoparticles camouflaged using self-proteins: overcoming immune recognition. J Mater Chem B 6:2204-2216
Zhang, Cun-Jin; Wang, Chenhui; Jiang, Meiling et al. (2018) Act1 is a negative regulator in T and B cells via direct inhibition of STAT3. Nat Commun 9:2745
Anderson, Ross W; Farokhniaee, AmirAli; Gunalan, Kabilar et al. (2018) Action potential initiation, propagation, and cortical invasion in the hyperdirect pathway during subthalamic deep brain stimulation. Brain Stimul 11:1140-1150
Liao, Xudong; Shen, Yuyan; Zhang, Rongli et al. (2018) Distinct roles of resident and nonresident macrophages in nonischemic cardiomyopathy. Proc Natl Acad Sci U S A 115:E4661-E4669
Sweet, David R; Fan, Liyan; Hsieh, Paishiun N et al. (2018) Krüppel-Like Factors in Vascular Inflammation: Mechanistic Insights and Therapeutic Potential. Front Cardiovasc Med 5:6
Otegbeye, Folashade; Ojo, Evelyn; Moreton, Stephen et al. (2018) Inhibiting TGF-beta signaling preserves the function of highly activated, in vitro expanded natural killer cells in AML and colon cancer models. PLoS One 13:e0191358
Shukla, Supriya; Richardson, Edward T; Drage, Michael G et al. (2018) Mycobacterium tuberculosis Lipoprotein and Lipoglycan Binding to Toll-Like Receptor 2 Correlates with Agonist Activity and Functional Outcomes. Infect Immun 86:
Chirieleison, Steven M; Rathkey, Joseph K; Abbott, Derek W (2018) Unique BIR domain sets determine inhibitor of apoptosis protein-driven cell death and NOD2 complex signal specificity. Sci Signal 11:
Dikina, Anna D; Alt, Daniel S; Herberg, Samuel et al. (2018) A Modular Strategy to Engineer Complex Tissues and Organs. Adv Sci (Weinh) 5:1700402
Choi, Elliot H; Suh, Susie; Sander, Christopher L et al. (2018) Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65. Hum Mol Genet 27:2225-2243

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