Abstract

This proposal requests continued funding of the predoctoral Training Program in Cell and Molecular Biology at the University of Washington and Fred Hutchinson Cancer Center (UW/FHCRC). Trainees in the program are chosen by a rigorous selection process that picks the top graduate students from three interdisciplinary programs and eight departmental programs. The major goal of this program is to train students in cell and molecular biology during their graduate career by exposing them to the wide range of research in this area. Students in the Training Program receive training beyond the standard graduate program through a monthly student presentation series that includes all of the trainees, an annual retreat that includes the trainees and their advisors, and through lectures supported by this program. This program plays an important role in training the next generation of scientists for academia and industry. The trainees have a strong record of success as shown by their publications in graduate school and the career choices they make after they leave graduate school.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007270-37
Application #
8099651
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Gindhart, Joseph G
Project Start
1975-07-01
Project End
2013-06-30
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
37
Fiscal Year
2011
Total Cost
$1,132,523
Indirect Cost

  Institution

Name
University of Washington
Department
Biochemistry
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Singh, Abhimanyu K; Nguyen, Thanh H; Vidovszky, Márton Z et al. (2018) Structure and N-acetylglucosamine binding of the distal domain of mouse adenovirus 2 fibre. J Gen Virol 99:1494-1508
Kursel, Lisa E; Malik, Harmit S (2018) The cellular mechanisms and consequences of centromere drive. Curr Opin Cell Biol 52:58-65
DaRosa, Paul A; Harrison, Joseph S; Zelter, Alex et al. (2018) A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-methylated DNA-Dependent Histone Ubiquitylation. Mol Cell 72:753-765.e6
Curran, Elizabeth C; Wang, Hui; Hinds, Thomas R et al. (2018) Zinc knuckle of TAF1 is a DNA binding module critical for TFIID promoter occupancy. Sci Rep 8:4630
Keller, Rachel B; Tran, Thao T; Pyott, Shawna M et al. (2018) Monoallelic and biallelic CREB3L1 variant causes mild and severe osteogenesis imperfecta, respectively. Genet Med 20:411-419
Dingens, Adam S; Acharya, Priyamvada; Haddox, Hugh K et al. (2018) Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV. PLoS Pathog 14:e1007159
LaCourse, Kaitlyn D; Peterson, S Brook; Kulasekara, Hemantha D et al. (2018) Conditional toxicity and synergy drive diversity among antibacterial effectors. Nat Microbiol 3:440-446
Cohen, Sara B; Gern, Benjamin H; Delahaye, Jared L et al. (2018) Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination. Cell Host Microbe 24:439-446.e4
Voillet, Valentin; Buggert, Marcus; Slichter, Chloe K et al. (2018) Human MAIT cells exit peripheral tissues and recirculate via lymph in steady state conditions. JCI Insight 3:
Brault, Michelle; Olsen, Tayla M; Martinez, Jennifer et al. (2018) Intracellular Nucleic Acid Sensing Triggers Necroptosis through Synergistic Type I IFN and TNF Signaling. J Immunol 200:2748-2756

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