The Cellular and Molecular Biology (CMB) training program offers doctoral candidates a broad-based education in molecular and cellular biology at institutions located within the Seattle biomedical corridor. Administered out of the University of Washington (UW), this interdisciplinary program also supports predoctoral trainees at the Fred Hutchinson Cancer Research Center (Fred Hutch) and partner institutions mostly located in the South Lake Union region of the city. The primary objectives of the CMB program are to recruit enthusiastic and motivated students who are passionate about the biomedical sciences and to provide personalized training across a range of disciplines pertaining to basic and translational aspects of molecular and cellular biology. These talented individuals have the opportunity to be mentored by 68 faculty members who are experts in a range of disciplines that include Biochemistry, Biophysical Structure and Design, Immunology, Microbiology, Molecular and Cellular Biology, Neuroscience, Pathology, Pharmacology, and Physiology and Biophysics. CMB trainees enter the program in years 2-4 of graduate school and are selected on academic record and performance in the written and oral components of the annual application competition. Trainees complete mandatory coursework in biostatistics and fundamentals of molecular biology; participate in the Biomedical Research Integrity Lecture series; attend a monthly student organized research conference with speaking and networking opportunities; and take part in the annual CMB Training Grant retreat. Traditionally, the CMB program has successfully partnered with several minority advocacy groups to promote diversity on all campuses. We continue to expand the under-represented minority (URM) footprint and are now emphasizing the recruitment and retention of students who are the first in their families to attend college (first generation) and students with disabilities. This innovative graduate training environment encourages trainees to pursue scientific excellence and endorses peer mentorship and the exploration of alternative career paths. The intended outcome is to nurture a diverse close-knit group of students who are equipped to become the next generation of scientific leaders.

Public Health Relevance

This program trains students to understand both the life of a cell at the molecular level and how this relates to human health. This is achieved through a combination of formal lectures, laboratory-based research, and group -learning experiences. The anticipated outcome of this educational experience is to nurture a diverse, close-knit group of students who are equipped to become the next generation of scientific leaders.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
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NIGMS Initial Review Group (TWD)
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Salazar, Desiree Lynn
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University of Washington
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Singh, Abhimanyu K; Nguyen, Thanh H; Vidovszky, Márton Z et al. (2018) Structure and N-acetylglucosamine binding of the distal domain of mouse adenovirus 2 fibre. J Gen Virol 99:1494-1508
Kursel, Lisa E; Malik, Harmit S (2018) The cellular mechanisms and consequences of centromere drive. Curr Opin Cell Biol 52:58-65
DaRosa, Paul A; Harrison, Joseph S; Zelter, Alex et al. (2018) A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-methylated DNA-Dependent Histone Ubiquitylation. Mol Cell 72:753-765.e6
Curran, Elizabeth C; Wang, Hui; Hinds, Thomas R et al. (2018) Zinc knuckle of TAF1 is a DNA binding module critical for TFIID promoter occupancy. Sci Rep 8:4630
Keller, Rachel B; Tran, Thao T; Pyott, Shawna M et al. (2018) Monoallelic and biallelic CREB3L1 variant causes mild and severe osteogenesis imperfecta, respectively. Genet Med 20:411-419
Dingens, Adam S; Acharya, Priyamvada; Haddox, Hugh K et al. (2018) Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV. PLoS Pathog 14:e1007159
LaCourse, Kaitlyn D; Peterson, S Brook; Kulasekara, Hemantha D et al. (2018) Conditional toxicity and synergy drive diversity among antibacterial effectors. Nat Microbiol 3:440-446
Cohen, Sara B; Gern, Benjamin H; Delahaye, Jared L et al. (2018) Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination. Cell Host Microbe 24:439-446.e4
Voillet, Valentin; Buggert, Marcus; Slichter, Chloe K et al. (2018) Human MAIT cells exit peripheral tissues and recirculate via lymph in steady state conditions. JCI Insight 3:
Brault, Michelle; Olsen, Tayla M; Martinez, Jennifer et al. (2018) Intracellular Nucleic Acid Sensing Triggers Necroptosis through Synergistic Type I IFN and TNF Signaling. J Immunol 200:2748-2756

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