Abstract

The purpose of the training program is to provide education in the pharmacological sciences and to train students in the philosophies, strategies and techniques of modern biological research. Graduates of this program in the past have obtained postdoctoral research experiences and then taken position at universities, government laboratories or industrial research laboratories. There are twenty-five faculty associated with the program and thirty-five students currently in the graduate program in pharmacological sciences. When a student has completed the requirements for the Ph.D. degree, he or she will: 1 Have a basic understanding of areas closely allied to pharmacological sciences including physiology, molecular biology and biochemistry. 2 Have broad background knowledge in pharmacological sciences. 3 Possess advanced knowledge in the specialty of the pharmacological sciences concerned with is or her dissertation research. 4 Have demonstrated the ability to design and perform research of high quality and communicate the results to others in a lucid manner. The program is characterized by the size and excellence of its faculty, the breadth and depth of research training opportunities and an exceptionally rich environment for education and research in the biological sciences.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007324-27
Application #
6620242
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Preusch, Peter C
Project Start
1975-07-01
Project End
2007-06-30
Budget Start
2003-07-01
Budget End
2004-06-30
Support Year
27
Fiscal Year
2003
Total Cost
$246,369
Indirect Cost

  Institution

Name
Yale University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520

  Publications

Luciano, Amelia K; Zhou, Wenping; Santana, Jeans M et al. (2018) CLOCK phosphorylation by AKT regulates its nuclear accumulation and circadian gene expression in peripheral tissues. J Biol Chem 293:9126-9136
MacLauchlan, Susan C; Calabro, Nicole E; Huang, Yan et al. (2018) HIF-1? represses the expression of the angiogenesis inhibitor thrombospondin-2. Matrix Biol 65:45-58
Moore, Lauren M; Wilkinson, Rachel; Altan, Mehmet et al. (2018) An assessment of neuronal calcium sensor-1 and response to neoadjuvant chemotherapy in breast cancer patients. NPJ Breast Cancer 4:6
Corbit, Kevin C; Camporez, João Paulo G; Edmunds, Lia R et al. (2018) Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling. Diabetes 67:208-221
Greenlee, Etienne B; Stav, Shira; Atilho, Ruben M et al. (2018) Challenges of ligand identification for the second wave of orphan riboswitch candidates. RNA Biol 15:377-390
Miller, Chad J; Turk, Benjamin E (2018) Homing in: Mechanisms of Substrate Targeting by Protein Kinases. Trends Biochem Sci 43:380-394
Perry, Curtis J; Muñoz-Rojas, Andrés R; Meeth, Katrina M et al. (2018) Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity. J Exp Med 215:877-893
Xiao, Qian; Wu, Jibo; Wang, Wei-Jia et al. (2018) DKK2 imparts tumor immunity evasion through ?-catenin-independent suppression of cytotoxic immune-cell activation. Nat Med 24:262-270
Iwamoto, Daniel V; Huehn, Andrew; Simon, Bertrand et al. (2018) Structural basis of the filamin A actin-binding domain interaction with F-actin. Nat Struct Mol Biol 25:918-927
Lacy, Michael; Kontos, Christos; Brandhofer, Markus et al. (2018) Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4. Sci Rep 8:5171

Showing the most recent 10 out of 91 publications