This is a proposal for the continued training of predoctoral graduate students in the area of molecular and cellular biology. The program is comprised of 45 Trainer-directed research programs and 15 trainee positions for graduate students, who will do their dissertation research in the Trainer labs. The graduate students are recruited primarily from four graduate programs (known as Graduate Groups), namely Biochemistry and Molecular Biology, Cell and Developmental Biology, Genetics and Microbiology, and are appointed to the Training Grant in their second year in the graduate program. The program is administered by a seven-person Executive Committee. The Training faculty will provide individual training programs, will be actively involved in recruiting graduate students to the Davis campus, and will provide courses in molecular and cell biology. There currently is (and will be) a highly successful Training Program Seminar Series in which extramural speakers are selected and hosted by the Trainees, an Annual Research Retreat, which is held at Lake Tahoe and serves as a forum for presentation of research seminars by students, postdoctoral fellows, and faculty members, and Brown-Bag lunches for the trainees with the Executive Committee to present and discuss their research. The Training Faculty and student Trainees will be evaluated on a yearly basis in order to ensure that the quality of the training programs, as well as Trainees, is maintained at a high level. Mechanisms for these evaluations are formalized and will be carried out by the Executive Committee. Evaluation of the Training Faculty emphasizes quality of the training programs (e.g. grant support, publication record and student training record), as well as a commitment to graduate education and the Program (e.g. attendance at retreats and seminars, participation in courses, and activity in Graduate Groups). Students will be evaluated on the basis of their research seminars, interviews, written report and publication record. The overall guiding principle is to support students from Training Grant funds who are highly productive.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007377-30
Application #
7250110
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Preusch, Peter C
Project Start
1983-07-01
Project End
2009-06-30
Budget Start
2007-07-01
Budget End
2009-06-30
Support Year
30
Fiscal Year
2007
Total Cost
$261,811
Indirect Cost
Name
University of California Davis
Department
Anatomy/Cell Biology
Type
Schools of Arts and Sciences
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
Kirmiz, Michael; Palacio, Stephanie; Thapa, Parashar et al. (2018) Remodeling neuronal ER-PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels. Mol Biol Cell 29:2410-2432
Coulson, Rochelle L; Yasui, Dag H; Dunaway, Keith W et al. (2018) Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex. Nat Commun 9:1616
Lal, Neeraj K; Nagalakshmi, Ugrappa; Hurlburt, Nicholas K et al. (2018) The Receptor-like Cytoplasmic Kinase BIK1 Localizes to the Nucleus and Regulates Defense Hormone Expression during Plant Innate Immunity. Cell Host Microbe 23:485-497.e5
Bishop, Hannah I; Cobb, Melanie M; Kirmiz, Michael et al. (2018) Kv2 Ion Channels Determine the Expression and Localization of the Associated AMIGO-1 Cell Adhesion Molecule in Adult Brain Neurons. Front Mol Neurosci 11:1
Bell, George R R; Collins, Sean R (2018) ""Rho""ing a Cellular Boat with Rearward Membrane Flow. Dev Cell 46:1-3
Huising, Mark O; Lee, Sharon; van der Meulen, Talitha (2018) Evidence for a Neogenic Niche at the Periphery of Pancreatic Islets. Bioessays 40:e1800119
Blain-Hartung, Matthew; Rockwell, Nathan C; Moreno, Marcus V et al. (2018) Cyanobacteriochrome-based photoswitchable adenylyl cyclases (cPACs) for broad spectrum light regulation of cAMP levels in cells. J Biol Chem 293:8473-8483
Ronning, Kaitryn E; Allina, Gabriel Peinado; Miller, Eric B et al. (2018) Loss of cone function without degeneration in a novel Gnat2 knock-out mouse. Exp Eye Res 171:111-118
van der Meulen, Talitha; Lee, Sharon; Noordeloos, Els et al. (2018) Artemether Does Not Turn ? Cells into ? Cells. Cell Metab 27:218-225.e4
Kirmiz, Michael; Vierra, Nicholas C; Palacio, Stephanie et al. (2018) Identification of VAPA and VAPB as Kv2 Channel-Interacting Proteins Defining Endoplasmic Reticulum-Plasma Membrane Junctions in Mammalian Brain Neurons. J Neurosci 38:7562-7584

Showing the most recent 10 out of 215 publications