Continued support is requested for an ongoing program in graduate research training in Genetics at the University of Oregon. Our goal is to produce creative, rigorous, and experimentally skilled scientists with an appreciation for the evolutionary, molecular, cellular, and developmental contexts of gene function and heredity.
We aim to help students develop the skills to lead research programs of their own, communicate science to the lay public, and teach the next generation of geneticists. Research training within an active laboratory provides the backbone of our program. We ensure a solid intellectual foundation by requiring trainees to take graduate level coursework in three core areas (molecular genetics, developmental genetics, and evolutionary genetics) and in statistics. Coursework is complemented in the first year by an intensive laboratory rotation program. We surround the lab and coursework with a wealth of enhancing and broadening experiences -- teaching, journal clubs, student research talks, seminar series by outside speakers, and more. Funds are requested for nine predoctoral trainee positions within a program that includes approximately 55 Ph.D. students and 23 faculty. The program brings together students and faculty from three research institutes (Institute of Molecular Biology, Institute of Neuroscience, and Institute of Ecology and Evolution) and three Departments (Biology, Chemistry, and Psychology). The program fosters interdisciplinary training via its highly collaborative group of training faculty, whose expertise spans the breadth of classical genetics, genomics, and allied disciplines. Students move easily between laboratories in the different departments and institutes due to the close proximity of all GTG faculty labs and to our faculty's commitment to minimizing bureaucratic barriers to such movement. The vast majority of former trainees have strong publication records and are employed in biomedical research and/or teaching.

Public Health Relevance

This application requests continued support for a Ph.D. program of research training in Genetics. A knowledge of how genes function, how they are regulated, and how they evolve is fundamental to virtually all problems in human physiology and disease. This program fosters interdisciplinary training via its highly collaborative group of training faculty, whose expertise spans the breadth of classical genetics, modern genetics and allied disciplines. We aim to help students develop into imaginative and rigorous research scientists who are equipped to lead research programs of their own, communicate science to the lay public, and teach the next generation of scientists.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
7T32GM007413-38
Application #
8884606
Study Section
Training and Workforce Development Subcommittee - D (TWD)
Program Officer
Haynes, Susan R
Project Start
1977-07-01
Project End
2018-06-30
Budget Start
2015-07-01
Budget End
2016-06-30
Support Year
38
Fiscal Year
2015
Total Cost
Indirect Cost
Name
University of Oregon
Department
Biochemistry
Type
Graduate Schools
DUNS #
City
Eugene
State
OR
Country
United States
Zip Code
97403
Carreira-Rosario, Arnaldo; Zarin, Aref Arzan; Clark, Matthew Q et al. (2018) MDN brain descending neurons coordinately activate backward and inhibit forward locomotion. Elife 7:
Jamieson, Kirsty; McNaught, Kevin J; Ormsby, Tereza et al. (2018) Telomere repeats induce domains of H3K27 methylation in Neurospora. Elife 7:
Kasimatis, Katja R; Phillips, Patrick C (2018) Rapid Gene Family Evolution of a Nematode Sperm Protein Despite Sequence Hyper-conservation. G3 (Bethesda) 8:353-362
Clark, Matthew Q; Zarin, Aref Arzan; Carreira-Rosario, Arnaldo et al. (2018) Neural circuits driving larval locomotion in Drosophila. Neural Dev 13:6
Kasimatis, Katja R; Moerdyk-Schauwecker, Megan J; Timmermeyer, Nadine et al. (2018) Proteomic and evolutionary analyses of sperm activation identify uncharacterized genes in Caenorhabditis nematodes. BMC Genomics 19:593
Loes, Andrea N; Bridgham, Jamie T; Harms, Michael J (2018) Coevolution of the Toll-Like Receptor 4 Complex with Calgranulins and Lipopolysaccharide. Front Immunol 9:304
Stagaman, Keaton; Cepon-Robins, Tara J; Liebert, Melissa A et al. (2018) Market Integration Predicts Human Gut Microbiome Attributes across a Gradient of Economic Development. mSystems 3:
Troll, Joshua V; Hamilton, M Kristina; Abel, Melissa L et al. (2018) Microbiota promote secretory cell determination in the intestinal epithelium by modulating host Notch signaling. Development 145:
Kasimatis, Katja R; Moerdyk-Schauwecker, Megan J; Phillips, Patrick C (2018) Auxin-Mediated Sterility Induction System for Longevity and Mating Studies in Caenorhabditis elegans. G3 (Bethesda) 8:2655-2662
Borne, Flora; Kasimatis, Katja R; Phillips, Patrick C (2017) Quantifying male and female pheromone-based mate choice in Caenorhabditis nematodes using a novel microfluidic technique. PLoS One 12:e0189679

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