The Predoctoral Genetics Training Program (GTP) is an interdisciplinary program that provides enriched genetics education for students receiving their Ph.D. degrees in six departments: Biological Chemistry, Ecology and Evolutionary biology (EEB), Human Genetics, Microbiology and Immunology, Molecular, Cellular and Developmental Biology (MCDB) and Pharmacology. Our goal is to train investigators who can apply disciplinary expertise to the new research opportunities of the genomic era. The GTP includes 62 faculty members and 21 trainees. During the current funding period, 38 students received the Ph.D. degree and the curriculum was updated to include training in computational biology and quantitative data analysis. Ongoing research projects range from microbial and viral gene regulation to yeast, plant, fly, mouse and human genetics, and functional genomics. Students are usually supported for their second and third years of graduate study. Most of our graduate students have gone on to productive research careers in academia and industry. Trainees benefit from a University environment that is strongly oriented towards graduate education, with a large and interactive research community that is among the top ten in NIH funding. University-supported core laboratories facilitate trainees'research by providing access to state-of -the-art technology including transgenic models, DNA sequencing, genotyping, and large-scale gene expression. The curriculum includes formal coursework in genetics and interactive seminars. Each year, trainees select four outstanding geneticists from outside the University to lecture on an area of interest. Our annual retreat features an invited keynote speaker and oral and poster presentations by current and former trainees. The GTP, one of the oldest NIH-supported training programs, continues to be a vital component of graduate education and biomedical research at the University of Michigan.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007544-33
Application #
7870398
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Haynes, Susan R
Project Start
1978-07-01
Project End
2013-06-30
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
33
Fiscal Year
2010
Total Cost
$468,833
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Genetics
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Abbott, Jamie A; Meyer-Schuman, Rebecca; Lupo, Vincenzo et al. (2018) Substrate interaction defects in histidyl-tRNA synthetase linked to dominant axonal peripheral neuropathy. Hum Mutat 39:415-432
Li, Yilai; Schroeder, Jeremy W; Simmons, Lyle A et al. (2018) Visualizing bacterial DNA replication and repair with molecular resolution. Curr Opin Microbiol 43:38-45
Kruger, Alyssa N; Ellison, Quinn; Brogley, Michele A et al. (2018) Male mice with large inversions or deletions of X-chromosome palindrome arms are fertile and express their associated genes during post-meiosis. Sci Rep 8:8985
Vallianatos, Christina N; Farrehi, Clara; Friez, Michael J et al. (2018) Altered Gene-Regulatory Function of KDM5C by a Novel Mutation Associated With Autism and Intellectual Disability. Front Mol Neurosci 11:104
Jordan, Valerie K; Fregeau, Brieana; Ge, Xiaoyan et al. (2018) Genotype-phenotype correlations in individuals with pathogenic RERE variants. Hum Mutat 39:666-675
Grill, Sherilyn; Tesmer, Valerie M; Nandakumar, Jayakrishnan (2018) The N Terminus of the OB Domain of Telomere Protein TPP1 Is Critical for Telomerase Action. Cell Rep 22:1132-1140
Moccia, Amanda; Martin, Donna M (2018) Nervous system development and disease: A focus on trithorax related proteins and chromatin remodelers. Mol Cell Neurosci 87:46-54
McCrone, John T; Woods, Robert J; Martin, Emily T et al. (2018) Stochastic processes constrain the within and between host evolution of influenza virus. Elife 7:
Bélanger, Catherine; Bérubé-Simard, Félix-Antoine; Leduc, Elizabeth et al. (2018) Dysregulation of cotranscriptional alternative splicing underlies CHARGE syndrome. Proc Natl Acad Sci U S A 115:E620-E629
Cheung, Leonard Y M; George, Akima S; McGee, Stacey R et al. (2018) Single-Cell RNA Sequencing Reveals Novel Markers of Male Pituitary Stem Cells and Hormone-Producing Cell Types. Endocrinology 159:3910-3924

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