The Tri-Institutional MD-PhD Program is a joint undertaking of Weill Cornell Medicine (WCM), The Rockefeller University (RU), and the Sloan Kettering Institute for Cancer Research (SKI). Its mission is to train biomedical investigators who: on the one hand, have advanced understanding of biomedical science and a mastery of contemporary research skills, which will allow them to undertake fundamental studies to elucidate basic biological processes pertaining to human disease; and, on the other hand, are well grounded in human biology, pathobiology and clinical medicine, which will equip them to transfer advances in basic research to the understanding, prevention, and treatment of human disease. The three institutions operate three graduate schools: Weill Cornell Graduate School of Medical Sciences (WCGS), a joint undertaking between WCM and SKI; the David Rockefeller Graduate School at RU; and the Gerstner Graduate School of Biomedical Sciences (GSK) at SKI. The Tri-Institutional MD-PhD Program was formed in 1991, when two independent MD-PhD Programs, the WCM-RU Program and the WCM-WCGS Program, were joined to form the present program. GSK became part of the Program in 2009. MSTP trainees complete all requirements for the MD degree at WCM. They receive their PhD training in research laboratories in the three research institutions and receive their PhD degree from GSK, RU or WCGS. Accepted trainees arrive in early July before the start of medical school. During the first two years in the Program they complete their medical school course, take two graduate level courses designed for MD-PhD students, and complete three research rotations (in three different laboratories) before they settle into their thesis laboratory. When the students choose a research laboratory they enroll in the graduate school with which their thesis mentor is associated. The graduate course and thesis requirements are comparable for all MD-PhD students, irrespective of the graduate school in which they are matriculated?and the students can cross register and take courses for credit in any of the graduate schools. At the end of their research training, after they have defended their thesis, the students return to complete their clinical training at WMC. The present application requests funds to continue MD-PhD training at the three institutions beyond Year 45 (the predecessor WCMC-RU Program was formed in 1972; it received NIH funding in 1974). In its current iteration, the Program brings together faculty in more than 250 independent research laboratories. 379 MD- PhDs have graduated from the Tri-Institutional MD-PhD Program and its predecessors; currently there are 137 students in the Program. The current trainees come from 55 undergraduate schools. Their average GPA is 3.75. 94% of the graduates pursue post-graduate clinical training; of the 305 graduates who have completed their training, 258 (85%) have appointments in medical schools, research institutes or biotech/pharma.
The increasing pace at which biomedical research advances increases, means that there is a greater need than ever for physicians who have received the rigorous research training that is required in order to work effectively at important problems at the intersection between clinical medicine and laboratory science?and thereby contribute toward improving health and enhancing the quality of life by reducing disability and death from disease. The goal of the Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional Medical Scientist Training Program is to identify, train and mentor a diverse group of outstanding men and women to become the future leaders in biomedical research and patient care?as scientists, educators and clinicians.
|Shipman, William D; Chyou, Susan; Ramanathan, Anusha et al. (2018) A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity. Sci Transl Med 10:|
|Geary, Clair D; Krishna, Chirag; Lau, Colleen M et al. (2018) Non-redundant ISGF3 Components Promote NK Cell Survival in an Auto-regulatory Manner during Viral Infection. Cell Rep 24:1949-1957.e6|
|Perez, R K; Kang, R; Chen, R et al. (2018) Computational Oncology. J Oncopathol Clin Res 2:|
|Alabi, Rolake O; Farber, Gregory; Blobel, Carl P (2018) Intriguing Roles for Endothelial ADAM10/Notch Signaling in the Development of Organ-Specific Vascular Beds. Physiol Rev 98:2025-2061|
|Guiberson, Noah Guy Lewis; Pineda, André; Abramov, Debra et al. (2018) Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones. Nat Commun 9:3986|
|Zafra, Maria Paz; Schatoff, Emma M; Katti, Alyna et al. (2018) Optimized base editors enable efficient editing in cells, organoids and mice. Nat Biotechnol 36:888-893|
|Hobbs, Gabriela S; Hanasoge Somasundara, Amritha Varshini; Kleppe, Maria et al. (2018) Hsp90 inhibition disrupts JAK-STAT signaling and leads to reductions in splenomegaly in patients with myeloproliferative neoplasms. Haematologica 103:e5-e9|
|Azimzadeh, Julien B; Fabella, Brian A; Kastan, Nathaniel R et al. (2018) Thermal Excitation of the Mechanotransduction Apparatus of Hair Cells. Neuron 97:586-595.e4|
|Gejman, Ron S; Chang, Aaron Y; Jones, Heather F et al. (2018) Rejection of immunogenic tumor clones is limited by clonal fraction. Elife 7:|
|Robinson, Christopher L; Chong, Angie C N; Ashbrook, Alison W et al. (2018) Male germ cells support long-term propagation of Zika virus. Nat Commun 9:2090|
Showing the most recent 10 out of 520 publications