The goal of the University of Michigan Medical Scientist Training Program is to train physician scientists primarily for careers in academic medicine with a focus on basic biomedical research. The U of Michigan Medical Center is one of the world's largest one-site complexes devoted to health education, research and patient care. There are over 1.8 million sq ft of space dedicated to education and laboratory research. In addition, a new research building is just starting to be occupied, and another new research building will begin occupancy in 2005. The Michigan MSTP provides an integrated curriculum of M.D./Ph.D. training. Matriculants have a strong history of academic success and research experience, and are graduates of outstanding colleges from all parts of the U.S. There are currently 84 trainees and 97 graduates. The curriculum begins with the two basic science years of medical school. A graduate level biochemistry course is taken as part of the 1st year of medical school. Trainees undertake a research rotation after the 1st year of medical school and one or two rotations after the 2nd year. Trainees select a Ph.D. field during the 2nd year of medical school;core participating departments include bioinformatics, biological chemistry, biophysics, cell &developmental biology, cellular &molecular biology, chemical biology, human genetics, immunology, medicinal chemistry, microbiology &immunology, molecular &integrative physiology, neuroscience, pathology, and pharmacology. Other fields are possible, e.g., biomedical engineering. Trainees take a leave of absence from medical school typically after the 2nd year to continue graduate studies full time. Upon successful completion of the thesis defense, trainees complete their clinical training. The 3rd year of medical school can be entered any month within the first half of the academic year to accommodate variations in thesis defense dates, and the 4th year of medical school is truncated to 6 months. Total training is typically 7 to 8 years. There are monthly program activities including seminars, social events and an annual scientific retreat.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007863-30
Application #
7650087
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Shapiro, Bert I
Project Start
1980-08-01
Project End
2010-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
30
Fiscal Year
2009
Total Cost
$1,667,298
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Zhang, Peng; Kuang, Henry; He, Yanlin et al. (2018) NRG1-Fc improves metabolic health via dual hepatic and central action. JCI Insight 3:
Kamran, Neha; Chandran, Mayuri; Lowenstein, Pedro R et al. (2018) Immature myeloid cells in the tumor microenvironment: Implications for immunotherapy. Clin Immunol 189:34-42
Singhal, Udit; Wang, Yugang; Henderson, James et al. (2018) Multigene Profiling of CTCs in mCRPC Identifies a Clinically Relevant Prognostic Signature. Mol Cancer Res 16:643-654
Li, Ziru; Hardij, Julie; Bagchi, Devika P et al. (2018) Development, regulation, metabolism and function of bone marrow adipose tissues. Bone 110:134-140
Nath, Samir R; Yu, Zhigang; Gipson, Theresa A et al. (2018) Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. J Clin Invest 128:3630-3641
Toubai, Tomomi; Rossi, Corinne; Tawara, Isao et al. (2018) Murine Models of Steroid Refractory Graft-versus-Host Disease. Sci Rep 8:12475
Wang, Charles Y; Dawid, Suzanne (2018) Mobilization of Bacteriocins during Competence in Streptococci. Trends Microbiol 26:389-391
Wong, Amanda O; Marthi, Matangi; Mendel, Zachary I et al. (2018) Renitence vacuoles facilitate protection against phagolysosomal damage in activated macrophages. Mol Biol Cell 29:657-668
Schofield, Heather K; Zeller, Jörg; Espinoza, Carlos et al. (2018) Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma. JCI Insight 3:
Adams, Caroline; Stroberg, Wylie; DeFazio, Richard A et al. (2018) Gonadotropin-Releasing Hormone (GnRH) Neuron Excitability Is Regulated by Estradiol Feedback and Kisspeptin. J Neurosci 38:1249-1263

Showing the most recent 10 out of 402 publications