The goal of the University of Michigan Medical Scientist Training Program is to train physician scientists primarily for careers in academic medicine with a focus on basic biomedical research. Such individuals are uniquely positioned to bridge the gap between basic and clinical medicine, and hence to connect basic discoveries to improvements in human health. The U of Michigan Medical Center is one of the world's largest one-site complexes devoted to health education, research and patient care. There are over 2.6 million sq ft of space dedicated to education and laboratory research. The Michigan MSTP provides an integrated curriculum of M.D./Ph.D. training. Matriculants have a strong history of academic success and research experience, and are graduates of outstanding colleges from all parts of the U.S. There are currently 82 trainees and 141 graduates. The curriculum begins with the two basic science years of medical school. A graduate level biochemistry course is taken as part of the 1st year of medical school. Trainees undertake a research rotation after the 1st year of medical school and one or two rotations after the 2nd year. Trainees select a Ph.D. field during the 2nd year of medical school;core participating departments include Bioinformatics, Biological Chemistry, Biophysics, Cell &Developmental Biology, Cellular &Molecular Biology, Chemical Biology, Human Genetics, Immunology, Medicinal Chemistry, Microbiology &Immunology, Molecular &Cellular Pathology, Molecular &Integrative Physiology, Neuroscience, and Pharmacology. Other fields are possible;for example, currently there are trainees in several departments in our Schools of Engineering and Public Health. Trainees take a leave of absence from medical school typically after the 2nd year or after the first 3 months of the 3rd year to continue graduate studies full time. Trainees can participate in clinical preceptorships during their research years. Upon successful completion of the thesis defense, trainees complete their clinical training. The 3rd year of medical school can be entered any month within the first half of the academic year to accommodate variations in thesis defense dates, and the 4th year of medical school is truncated to 20 weeks. Total training is typically 7 to 8 years. There are monthly program activities including seminars, social events and an annual scientific retreat.

Public Health Relevance

Trainees receive both an M.D. and a Ph.D. in a medically-relevant field of research. Program graduates are optimally prepared to establish research-based careers in which the goal is to improve the public's health.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007863-35
Application #
8686863
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Preusch, Peter
Project Start
1980-08-01
Project End
2015-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
35
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Toubai, Tomomi; Rossi, Corinne; Tawara, Isao et al. (2018) Murine Models of Steroid Refractory Graft-versus-Host Disease. Sci Rep 8:12475
Wang, Charles Y; Dawid, Suzanne (2018) Mobilization of Bacteriocins during Competence in Streptococci. Trends Microbiol 26:389-391
Wong, Amanda O; Marthi, Matangi; Mendel, Zachary I et al. (2018) Renitence vacuoles facilitate protection against phagolysosomal damage in activated macrophages. Mol Biol Cell 29:657-668
Schofield, Heather K; Zeller, Jörg; Espinoza, Carlos et al. (2018) Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma. JCI Insight 3:
Adams, Caroline; Stroberg, Wylie; DeFazio, Richard A et al. (2018) Gonadotropin-Releasing Hormone (GnRH) Neuron Excitability Is Regulated by Estradiol Feedback and Kisspeptin. J Neurosci 38:1249-1263
Hacker, Kari E; Bolland, Danielle E; Tan, Lijun et al. (2018) The DEK Oncoprotein Functions in Ovarian Cancer Growth and Survival. Neoplasia 20:1209-1218
Schultz, Mark L; Krus, Kelsey L; Kaushik, Susmita et al. (2018) Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD. Nat Commun 9:3671
Pappas, Samuel S; Li, Jay; LeWitt, Tessa M et al. (2018) A cell autonomous torsinA requirement for cholinergic neuron survival and motor control. Elife 7:
Jun, Heejin; Yu, Hui; Gong, Jianke et al. (2018) An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling. Nat Med 24:814-822
Bagchi, Devika P; Forss, Isabel; Mandrup, Susanne et al. (2018) SnapShot: Niche Determines Adipocyte Character I. Cell Metab 27:264-264.e1

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