Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007964-13
Application #
2167003
Study Section
Genetic Basis of Disease Review Committee (GBD)
Project Start
1981-08-01
Project End
1995-06-30
Budget Start
1994-07-01
Budget End
1995-06-30
Support Year
13
Fiscal Year
1994
Total Cost
Indirect Cost
Name
State University New York Stony Brook
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Torres, AnnMarie; Luke, Joanna D; Kullas, Amy L et al. (2016) Asparagine deprivation mediated by Salmonella asparaginase causes suppression of activation-induced T cell metabolic reprogramming. J Leukoc Biol 99:387-98
Vink, Elizabeth I; Zheng, Yueting; Yeasmin, Rukhsana et al. (2015) Impact of Adenovirus E4-ORF3 Oligomerization and Protein Localization on Cellular Gene Expression. Viruses 7:2428-49
Nakayama, Takuya; Fish, Margaret B; Fisher, Marilyn et al. (2013) Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis. Genesis 51:835-43
Lachance, Joseph; Jung, Lawrence; True, John R (2013) Genetic background and GxE interactions modulate the penetrance of a naturally occurring wing mutation in Drosophila melanogaster. G3 (Bethesda) 3:1893-901
Kullas, Amy L; McClelland, Michael; Yang, Hee-Jeong et al. (2012) L-asparaginase II produced by Salmonella typhimurium inhibits T cell responses and mediates virulence. Cell Host Microbe 12:791-8
Lachance, Joseph; Johnson, Norman A; True, John R (2011) The population genetics of X-autosome synthetic lethals and steriles. Genetics 189:1011-27
Lachance, Joseph; True, John R (2010) X-autosome incompatibilities in Drosophila melanogaster: tests of Haldane's rule and geographic patterns within species. Evolution 64:3035-46
Lachance, Joseph (2010) Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations. BMC Med Genomics 3:57
Lachance, Joseph (2009) Inbreeding, pedigree size, and the most recent common ancestor of humanity. J Theor Biol 261:238-47
Lachance, Joseph (2009) Detecting selection-induced departures from Hardy-Weinberg proportions. Genet Sel Evol 41:15

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