The Genetics Graduate Program is an inter-institutional program between Stony Brook University, Cold Spring Harbor Laboratory and Brookhaven National Laboratory that offers superb opportunities for graduate training. The inter-institutional spirit of cooperation is evident in the participation of faculty from all three institutions in the courses, journal clubs and student research seminars included within the training program. Although the particular courses a student will take vary, depending on their background and their area of specialization, all students receive a working knowledge of all major areas of genetics. Program students have unique opportunities to participate in seminar programs and symposia at all three institutions, including the wonderfully varied meetings and short-courses offered at Cold Spring Harbor, and have direct access to world-class research facilities such as the synchrotron light source at Brookhaven. A major strength of the Program is the diverse range of research expertise that is provided by the 98 faculty from these three institutions, including 12 different academic Departments at Stony Brook. This breadth, which reflects the ever-expanding role of genetics in modern biology, includes significant strengths in the areas of bioinformatics, developmental biology, evolution, gene therapy, molecular and cellular biology, neurobiology, pathology and structural biology. The research opportunities extend from fundamental studies on classical animal, plant and microbial model systems, to cutting-edge research on processes such as behavior, cancer and other human diseases. The spirit of cooperation that is the guiding philosophy of the Genetics Program allows students to take full advantage of this enormous range of educational and research opportunities in a collegial environment that fosters interdisciplinary interactions. With vigorous support from Stony Brook, CSHL and BNL and with continuous NIH support since 1981, the Genetics Program has a distinguished record in the quality of students that are attracted, their accomplishments during their graduate career, and their record in launching successful careers in academia and industry. This application requests an additional five years of support for this outstanding Program.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007964-24
Application #
6898719
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Rhoades, Marcus M
Project Start
1981-08-01
Project End
2008-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
24
Fiscal Year
2005
Total Cost
$217,313
Indirect Cost
Name
State University New York Stony Brook
Department
Biochemistry
Type
Schools of Medicine
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Torres, AnnMarie; Luke, Joanna D; Kullas, Amy L et al. (2016) Asparagine deprivation mediated by Salmonella asparaginase causes suppression of activation-induced T cell metabolic reprogramming. J Leukoc Biol 99:387-98
Vink, Elizabeth I; Zheng, Yueting; Yeasmin, Rukhsana et al. (2015) Impact of Adenovirus E4-ORF3 Oligomerization and Protein Localization on Cellular Gene Expression. Viruses 7:2428-49
Nakayama, Takuya; Fish, Margaret B; Fisher, Marilyn et al. (2013) Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis. Genesis 51:835-43
Lachance, Joseph; Jung, Lawrence; True, John R (2013) Genetic background and GxE interactions modulate the penetrance of a naturally occurring wing mutation in Drosophila melanogaster. G3 (Bethesda) 3:1893-901
Kullas, Amy L; McClelland, Michael; Yang, Hee-Jeong et al. (2012) L-asparaginase II produced by Salmonella typhimurium inhibits T cell responses and mediates virulence. Cell Host Microbe 12:791-8
Lachance, Joseph; Johnson, Norman A; True, John R (2011) The population genetics of X-autosome synthetic lethals and steriles. Genetics 189:1011-27
Lachance, Joseph; True, John R (2010) X-autosome incompatibilities in Drosophila melanogaster: tests of Haldane's rule and geographic patterns within species. Evolution 64:3035-46
Lachance, Joseph (2010) Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations. BMC Med Genomics 3:57
Lachance, Joseph (2009) Inbreeding, pedigree size, and the most recent common ancestor of humanity. J Theor Biol 261:238-47
Lachance, Joseph (2009) Detecting selection-induced departures from Hardy-Weinberg proportions. Genet Sel Evol 41:15

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