The Pharmacology Graduate Training Program's mission is to prepare PhD scientists in fields of pharmacology for careers in academic and industrial research, governmental agencies and a variety of professional paths Our mission is accomplished by training our Ph.D. students to be critical thinkers, embracing innovation and creativity to advance scholarship and scientific discovery. This training program is the only one at the University of Pennsylvania that trains predoctoral graduate students in fundamentals of Pharmacology. Current areas of research and training in the PGG are Neuropharmacology, Cell Signaling, Pharmacological Chemistry, Cancer Pharmacology, Cardiovascular Pharmacology, Pharmacogenetics, Environmental Toxicology, and Translational Medicine. The PGG offers 14 graduate-level courses in Pharmacology and two recently developed workshops on ?Professional Skills? and ?Grant Writing/Candidacy Exam? preparation. Over the past five years the total number of students in the program has remained relatively constant with the current census at 68 (64 TGE) and the number of faculty trainers has remained near 60. Due to the training requirements associated with the training program, all predoctoral trainees supported by the training grant are in the PGG. We request support for 12 predoctoral training positions for the next 5 years. The pool of students available for appointment to the training program comprises all US residents or students with permanent resident status in the PGG. We support students for one to two years in Year 2 and 3 as most coursework and training workshops occurs during these years however all students supported with this training program continue to participate and enjoy the training related activities until awarding of their PhD.

Public Health Relevance

The Pharmacology Graduate Training Program at the University of Pennsylvania is in its 33rd year, and over this time has produced 229 well-trained pharmacologists, who have made an impact in academia, pharmaceutical and biotechnology industries, regulatory agencies, and many other research related careers. The urgency to apply basic discoveries to the understanding and alleviation of human disease has never been greater. Thus, a major focus of our training program is on translational research, which is in many ways the essence of pharmacology

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
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NIGMS Initial Review Group (TWD)
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Koduri, Sailaja
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University of Pennsylvania
Schools of Medicine
United States
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Malik, Dania M; Rhoades, Seth; Weljie, Aalim (2018) Extraction and Analysis of Pan-metabolome Polar Metabolites by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS). Bio Protoc 8:
Allenby, Cheyenne; Falcone, Mary; Bernardo, Leah et al. (2018) Transcranial direct current brain stimulation decreases impulsivity in ADHD. Brain Stimul 11:974-981
Reilly, Sean W; Puentes, Laura N; Schmitz, Alexander et al. (2018) Synthesis and evaluation of an AZD2461 [18F]PET probe in non-human primates reveals the PARP-1 inhibitor to be non-blood-brain barrier penetrant. Bioorg Chem 83:242-249
Henrich, Ian C; Young, Robert; Quick, Laura et al. (2018) USP6 Confers Sensitivity to IFN-Mediated Apoptosis through Modulation of TRAIL Signaling in Ewing Sarcoma. Mol Cancer Res 16:1834-1843
Ren, Xianfeng; Schmidt, William; Huang, Yiyuan et al. (2018) Fropofol decreases force development in cardiac muscle. FASEB J 32:4203-4213
Chuang, Edward; Hori, Acacia M; Hesketh, Christina D et al. (2018) Amyloid assembly and disassembly. J Cell Sci 131:
Wang, Amber W; Wangensteen, Kirk J; Wang, Yue J et al. (2018) TRAP-seq identifies cystine/glutamate antiporter as a driver of recovery from liver injury. J Clin Invest 128:2297-2309
Ojiaku, Christie A; Cao, Gaoyuan; Zhu, Wanqu et al. (2018) TGF-?1 Evokes Human Airway Smooth Muscle Cell Shortening and Hyperresponsiveness via Smad3. Am J Respir Cell Mol Biol 58:575-584
Jackson, Dan P; Ting, Jenhao H; Pozniak, Paul D et al. (2018) Identification and characterization of two novel alternatively spliced E2F1 transcripts in the rat CNS. Mol Cell Neurosci 92:1-11
Rhoades, Seth D; Nayak, Katrina; Zhang, Shirley L et al. (2018) Circadian- and Light-driven Metabolic Rhythms in Drosophila melanogaster. J Biol Rhythms 33:126-136

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