The Cell and Molecular Biology (CMB) Training Program at the University of Texas Southwestern Medical Center at Dallas fosters the development of Ph.D. scientists with the skills and resources necessary to succeed as independent researchers in a rapidly changing scientific environment. In response to this changing environment, the CMB Training Program at UT Southwestern is largely driven by the trainees. The program focuses on Cellular and Molecular Biology as it applies to medical advances, reflecting the research interests of the students and the laboratories in which they train. It provides formal training in statistical analysis of biological data and emphasizes the importance of collaborative research in acquiring the breadth of knowledge and skills needed for the rapid pace of developments. The program offers unique small group settings for the trainees to acquire new knowledge, form scientific hypotheses, and critically analyze data. Students compete for positions in this training program by writing a research summary and personal statement about why they would like to participate. The application process is open to students in their second or later year of a Ph.D. program or in their first or second graduate school year of the MSTP program. The new trainees are chosen by the CMB Steering Committee based on personal statement, motivation, and diversity of research topic. Most students remain in the training program for 3 years, usually including one year of advanced didactic training and up to 2 years of independent research. Currently, there are 14 granted slots, with 13 funded due to budget constraints of the NIH. The interdisciplinary, student-focused CMB program is structured to stimulate the trainees'critical thinking and to present novel opportunities to question and evaluate cellular and molecular research important for human health. This interdisciplinary training program provides didactic and laboratory training of students in a range of fields that encompass many aspects of cell and molecular biology, culminating in the Ph.D. degree. Multiple training experiences include a round table journal club covering diverse scientific questions and methodologies and designed to stimulate critical analysis, breadth of thinking, and dialog;a faculty seminar series that combines a discussion of career path and cutting edge research;a poster with all CMB faculty;and a retreat in which students'present their ongoing research and plan the following year's activities. Scientists equipped with skills provided by this training program will perform inspired research that crosses disciplines to make discoveries that benefit human health in the future.

Public Health Relevance

This training program develops critical thinking, scientific breadth, and exploration of novel technologies to investigate important questions in cellular and molecular biology related to human health. Scientists equipped with these tools, habits of mind and resourcefulness will make valuable discoveries that enhance quality of life in the future. Students are chosen to maintain a diversity of research interest and have major input into aspects of their own training.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
2T32GM008203-26A1
Application #
8607856
Study Section
(TWD)
Program Officer
Gindhart, Joseph G
Project Start
1987-07-01
Project End
2019-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
26
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Sharma, Ankit X; Quittner-Strom, Ezekiel B; Lee, Young et al. (2018) Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice. Cell Rep 22:1760-1773
Salinas, Victor H; Ranganathan, Rama (2018) Coevolution-based inference of amino acid interactions underlying protein function. Elife 7:
Shao, Mengle; Vishvanath, Lavanya; Busbuso, Napoleon C et al. (2018) De novo adipocyte differentiation from Pdgfr?+ preadipocytes protects against pathologic visceral adipose expansion in obesity. Nat Commun 9:890
Hepler, Chelsea; Shan, Bo; Zhang, Qianbin et al. (2018) Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice. Elife 7:
Chang, Chi-Lun; Chen, Yu-Ju; Quintanilla, Carlo Giovanni et al. (2018) EB1 binding restricts STIM1 translocation to ER-PM junctions and regulates store-operated Ca2+ entry. J Cell Biol 217:2047-2058
Walsh Jr, Richard M; Roh, Soung-Hun; Gharpure, Anant et al. (2018) Structural principles of distinct assemblies of the human ?4?2 nicotinic receptor. Nature 557:261-265
McMillan, Elizabeth A; Ryu, Myung-Jeom; Diep, Caroline H et al. (2018) Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer. Cell 173:864-878.e29
A?aƧ, Didem; Estrada, Leonardo D; Maples, Robert et al. (2018) The ?2-adrenergic receptor controls inflammation by driving rapid IL-10 secretion. Brain Behav Immun 74:176-185
Johnston, Andrea; Wang, Zhigao (2018) Necroptosis: MLKL Polymerization. J Nat Sci 4:
Zhu, Shaotong; Noviello, Colleen M; Teng, Jinfeng et al. (2018) Structure of a human synaptic GABAA receptor. Nature 559:67-72

Showing the most recent 10 out of 119 publications