Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
2T32GM008270-11
Application #
2550519
Study Section
Special Emphasis Panel (ZGM1-BRT-5 (01))
Project Start
1988-09-30
Project End
2003-06-30
Budget Start
1998-07-01
Budget End
1999-06-30
Support Year
11
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Organized Research Units
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Tripathi, Ashootosh; Park, Sung Ryeol; Sikkema, Andrew P et al. (2018) A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ. Chembiochem 19:1595-1600
Skiba, Meredith A; Sikkema, Andrew P; Moss, Nathan A et al. (2018) Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module. ACS Chem Biol 13:1640-1650
Castle, Brian T; McCubbin, Seth; Prahl, Louis S et al. (2017) Mechanisms of kinetic stabilization by the drugs paclitaxel and vinblastine. Mol Biol Cell 28:1238-1257
Cai, Yingying; Liu, Yuting; Culhane, Kelly J et al. (2017) Purification of family B G protein-coupled receptors using nanodiscs: Application to human glucagon-like peptide-1 receptor. PLoS One 12:e0179568
Skiba, Meredith A; Sikkema, Andrew P; Moss, Nathan A et al. (2017) A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit. ACS Chem Biol 12:3039-3048
Horowitz, Scott; Koepnick, Brian; Martin, Raoul et al. (2016) Determining crystal structures through crowdsourcing and coursework. Nat Commun 7:12549
Kim, Laura Y; Thompson, Peter M; Lee, Hyunna T et al. (2016) The Structural Basis of Actin Organization by Vinculin and Metavinculin. J Mol Biol 428:10-25
DeVree, Brian T; Mahoney, Jacob P; VĂ©lez-Ruiz, Gisselle A et al. (2016) Allosteric coupling from G protein to the agonist-binding pocket in GPCRs. Nature 535:182-6
Taylor, Veronica G; Bommarito, Paige A; Tesmer, John J G (2016) Structure of the Regulator of G Protein Signaling 8 (RGS8)-G?q Complex: MOLECULAR BASIS FOR G? SELECTIVITY. J Biol Chem 291:5138-45
Howard, Michael J; Karasik, Agnes; Klemm, Bradley P et al. (2016) Differential substrate recognition by isozymes of plant protein-only Ribonuclease P. RNA 22:782-92

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