Abstract

INSTITUTIONAL NATIONAL RESEARCH SERVICE AWARD (Substitute Page) TABLE OF CONTENTS Page Numbe_ Face Page Description and Personnel, Table of Contents (Form Pages 1, 2, and this NRSA Substitute Form Page 3) ................................................................. 1- 3 Detailed Budget for Initial Budget Period (NRSA Substitute Form Page 4) ....................................... 4 Budget for Entire Proposed Period of Support (NRSA Substitute Form Page 5) .............................. 5 Biographical Sketch--Principal investigator/Program Director (Not to exceed four pages) .......... 6 Other Biographical Sketches (Not to exceed four pages for each) .................................................... Resources .................................................................................................................................................. 8 Research Training Program Plan Introduction to Revised Application (Not to exceed 3 pages) ......................................................................................................... Introduction to Supplemental Application (Not to exceed one page) .............................................................................................. A. Background ....................................................................................................................................................................... 9 B. Program Plan ..................................................................................................................................................................... 12 1. Program Direction ........................................ 12 2. Program Faculty .................................................................................... (Items A-D: not to exceed 25 pages, 13 3. Proposed Training ........................................ excluding tables*) 14 4. Trainee Candidates ................................................................................................................................... 22 C. Recruitment of Individuals from Underrepresented Racial/Ethnic Groups .............................................................................. 23 D. Responsible Conduct of Research ................................................................................................................................... 27 E. Progress Report (Competing Continuation Applications Only) ............................................................................................ 27 F. Human Subjects ................................................................................................................................................................ 31 Protection of Human Subjects (Required if Item 4 on the Face Page is marked '_'es"""""""") Inclusion of Women (Required if Item 4 on the Face Page is marked """"""""Yes"""""""") ............................................................... Inclusion of Minorities (Required if Item 4 on the Face Page is marked '_(es"""""""") ............................................................... Inclusion of Children (Required if Item 4 on the Face Page is marked """"""""Yes"""""""") ............................................................... Data and Safety Monitoring Plan (Required if Item 4 on the Face Page is marked """"""""Yes"""""""" anda Phase I, II, or III clinical trial is proposed) ............................................................................................................................................................ G. Vertebrate Animals ............................................................................................................................................................ 31 H. Consortium/Contractual Arrangements .............................................................................................................................. Checklist .................................................................................................................................................... 32 *Type density and size must conform to limits provided in PHS 398 Specific Instructions. Appendix (Five collated sets. No page numbering necessary for Appendix.) D ACphpecnkdixif is included PHS 398 (Rev. 05/01) (Form Page 3) Page NRSA Substitute Page Number pages consecutively at the bottom throughout the application. Do not use suffixes such as 3a, 3b. NN

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
3T32GM008276-20S1
Application #
7636410
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Flicker, Paula F
Project Start
1988-09-30
Project End
2009-06-30
Budget Start
2007-07-01
Budget End
2009-06-30
Support Year
20
Fiscal Year
2008
Total Cost
$153,659
Indirect Cost

  Institution

Name
University of Illinois Urbana-Champaign
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
041544081
City
Champaign
State
IL
Country
United States
Zip Code
61820

  Publications

Mahinthichaichan, Paween; Morris, Dylan M; Wang, Yi et al. (2018) Selective Permeability of Carboxysome Shell Pores to Anionic Molecules. J Phys Chem B 122:9110-9118
Mahinthichaichan, Paween; Gennis, Robert B; Tajkhorshid, Emad (2018) Cytochrome aa3 Oxygen Reductase Utilizes the Tunnel Observed in the Crystal Structures To Deliver O2 for Catalysis. Biochemistry 57:2150-2161
Mahinthichaichan, Paween; Gennis, Robert B; Tajkhorshid, Emad (2018) Bacterial denitrifying nitric oxide reductases and aerobic respiratory terminal oxidases use similar delivery pathways for their molecular substrates. Biochim Biophys Acta Bioenerg 1859:712-724
Barclay, Alexander M; Dhavale, Dhruva D; Courtney, Joseph M et al. (2018) Resonance assignments of an ?-synuclein fibril prepared in Tris buffer at moderate ionic strength. Biomol NMR Assign 12:195-199
Reed, Julian H; Shi, Yelu; Zhu, Qianhong et al. (2017) Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism. J Am Chem Soc 139:12209-12218
Mahinthichaichan, Paween; Gennis, Robert B; Tajkhorshid, Emad (2016) All the O2 Consumed by Thermus thermophilus Cytochrome ba3 Is Delivered to the Active Site through a Long, Open Hydrophobic Tunnel with Entrances within the Lipid Bilayer. Biochemistry 55:1265-78
Desai, Janish; Liu, Yi-Liang; Wei, Hongli et al. (2016) Structure, Function, and Inhibition of Staphylococcus aureus Heptaprenyl Diphosphate Synthase. ChemMedChem 11:1915-23
Tuttle, Marcus D; Comellas, Gemma; Nieuwkoop, Andrew J et al. (2016) Solid-state NMR structure of a pathogenic fibril of full-length human ?-synuclein. Nat Struct Mol Biol 23:409-15
Tuttle, Marcus D; Courtney, Joseph M; Barclay, Alexander M et al. (2016) Preparation of Amyloid Fibrils for Magic-Angle Spinning Solid-State NMR Spectroscopy. Methods Mol Biol 1345:173-83
Sun, Chang; Taguchi, Alexander T; Vermaas, Josh V et al. (2016) Q-Band Electron-Nuclear Double Resonance Reveals Out-of-Plane Hydrogen Bonds Stabilize an Anionic Ubisemiquinone in Cytochrome bo3 from Escherichia coli. Biochemistry 55:5714-5725

Showing the most recent 10 out of 82 publications