Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008365-12
Application #
6351060
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Jones, Warren
Project Start
1990-07-01
Project End
2005-06-30
Budget Start
2001-07-01
Budget End
2002-06-30
Support Year
12
Fiscal Year
2001
Total Cost
$115,490
Indirect Cost
Name
University of Iowa
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Ricker, Erica B; Aljaafari, Haydar A S; Bader, Trigg M et al. (2018) Thermal shock susceptibility and regrowth of Pseudomonas aeruginosa biofilms. Int J Hyperthermia 34:168-176
Mondal, Dibyendu; Koehn, Eric M; Yao, Jiajun et al. (2018) Chemo-enzymatic synthesis of the exocyclic olefin isomer of thymidine monophosphate. Bioorg Med Chem 26:2365-2371
Oppegard, Lisa M; Delgado, Justine L; Kulkarni, Chaitanya A et al. (2018) Novel N-1 substituted fluoroquinolones inhibit human topoisomerase I activity and exhibit anti-proliferative activity. Invest New Drugs :
Imai, Yumi; Fink, Brian D; Promes, Joseph A et al. (2018) Effect of a mitochondrial-targeted coenzyme Q analog on pancreatic ?-cell function and energetics in high fat fed obese mice. Pharmacol Res Perspect 6:e00393
Delgado, Justine L; Hsieh, Chao-Ming; Chan, Nei-Li et al. (2018) Topoisomerases as anticancer targets. Biochem J 475:373-398
Towle, Tyrell R; Kulkarni, Chaitanya A; Oppegard, Lisa M et al. (2018) Design, synthesis, and evaluation of novel N-1 fluoroquinolone derivatives: Probing for binding contact with the active site tyrosine of gyrase. Bioorg Med Chem Lett 28:1903-1910
Bain, Fletcher E; Fischer, Laura A; Chen, Ran et al. (2018) Single-Molecule Analysis of Replication Protein A-DNA Interactions. Methods Enzymol 600:439-461
Stockdale, David P; Beutler, John A; Wiemer, David F (2017) Synthesis of amide isosteres of schweinfurthin-based stilbenes. Bioorg Med Chem 25:5483-5489
Bodle, Christopher R; Mackie, Duncan I; Hayes, Michael P et al. (2017) Natural Products Discovered in a High-Throughput Screen Identified as Inhibitors of RGS17 and as Cytostatic and Cytotoxic Agents for Lung and Prostate Cancer Cell Lines. J Nat Prod 80:1992-2000
Kim, Keehyuk; Plapp, Bryce V (2017) Inversion of substrate stereoselectivity of horse liver alcohol dehydrogenase by substitutions of Ser-48 and Phe-93. Chem Biol Interact 276:77-87

Showing the most recent 10 out of 128 publications