This proposal requests funding continuation for the Predoctoral Biotechnology Training Program at Northwestern University (NU). This interdisciplinary and interdepartmental Program offers biotechnology training opportunities for a select group of Ph.D. students from four participating units: the departments of Biomedical and Chemical Engineering (ChE), the Chemistry department, and the Interdepartmental Biological Sciences (IBiS) graduate program. Research opportunities, chosen from among a wide array of laboratories in the life sciences, are complemented by a core interdisciplinary curriculum. Three- to 6-month industrial internships expose trainees to the industrial environment of modern biotechnology. All trainees and most preceptors participate in the IBiS, two-day, off-campus annual retreat, which allows extensive interactions among students and faculty from many disciplines and increases the cohesiveness of the trainee group. The Biotechnology research club, which meets once a month or more during the academic year and twice a month during the summer, is the forum where trainees and faculty present their research results to and interact with other students participating in the Program. Several other interdisciplinary research clubs (e.g. Biophysics Club, Biomaterials Club) provide trainees with additional opportunities to broaden their knowledge and perspective. Trainees organize and host biotechnology seminars that bring industrial and academic scientists to campus for a seminar and discussions with trainees. Students also take advantage of several other life sciences-related seminar programs on campus. Instruction in the responsible conduct of research is carried out primarily through the course """"""""Ethics in Biological Research"""""""". Trainees are recruited by the Program and the participating units, using posters, brochures, and WWW pages. Intensive efforts are made to recruit students from underrepresented groups, and have been quite successful. In the first 5 years of this Training Program a significant fraction of trainees has come from ChE because of the larger student-applicant pool. During the past 4 years, however, a diverse population of graduate students from BME, IBiS, and ChE has been supported in a balanced manner. The number of preceptors participating in the Program will increase from 18 to 31. An increase from 5 to 8 funded positions will support this expanded preceptor base and allow the support of some Chemistry students. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
2T32GM008449-11
Application #
6697614
Study Section
Special Emphasis Panel (ZGM1-BRT-1 (03))
Program Officer
Jones, Warren
Project Start
1993-09-01
Project End
2009-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
11
Fiscal Year
2004
Total Cost
$303,341
Indirect Cost
Name
Northwestern University at Chicago
Department
Engineering (All Types)
Type
Schools of Engineering
DUNS #
160079455
City
Evanston
State
IL
Country
United States
Zip Code
60201
Clevenger, Kenneth D; Ye, Rosa; Bok, Jin Woo et al. (2018) Interrogation of Benzomalvin Biosynthesis Using Fungal Artificial Chromosomes with Metabolomic Scoring (FAC-MS): Discovery of a Benzodiazepine Synthase Activity. Biochemistry 57:3237-3243
Evans, Kathryn S; Brady, Shannon C; Bloom, Joshua S et al. (2018) Shared Genomic Regions Underlie Natural Variation in Diverse Toxin Responses. Genetics 210:1509-1525
Finkle, Justin D; Wu, Jia J; Bagheri, Neda (2018) Windowed Granger causal inference strategy improves discovery of gene regulatory networks. Proc Natl Acad Sci U S A 115:2252-2257
Allen, Sean; Vincent, Michael; Scott, Evan (2018) Rapid, Scalable Assembly and Loading of Bioactive Proteins and Immunostimulants into Diverse Synthetic Nanocarriers Via Flash Nanoprecipitation. J Vis Exp :
Robey, Matthew T; Ye, Rosa; Bok, Jin Woo et al. (2018) Identification of the First Diketomorpholine Biosynthetic Pathway Using FAC-MS Technology. ACS Chem Biol 13:1142-1147
Su, Jimmy; Satchell, Simon C; Shah, Ramille N et al. (2018) Kidney decellularized extracellular matrix hydrogels: Rheological characterization and human glomerular endothelial cell response to encapsulation. J Biomed Mater Res A 106:2448-2462
Lewis, Phillip L; Su, Jimmy; Yan, Ming et al. (2018) Complex bile duct network formation within liver decellularized extracellular matrix hydrogels. Sci Rep 8:12220
Yu, Jessica S; Pertusi, Dante A; Adeniran, Adebola V et al. (2017) CellSort: a support vector machine tool for optimizing fluorescence-activated cell sorting and reducing experimental effort. Bioinformatics 33:909-916
Martinez, Andres F; McMahon, Richard D; Horner, Marc et al. (2017) A uniform-shear rate microfluidic bioreactor for real-time study of proplatelet formation and rapidly-released platelets. Biotechnol Prog 33:1614-1629
Amin, Devang R; Sugnaux, Caroline; Lau, King Hang Aaron et al. (2017) Size Control and Fluorescence Labeling of Polydopamine Melanin-Mimetic Nanoparticles for Intracellular Imaging. Biomimetics (Basel) 2:

Showing the most recent 10 out of 97 publications